SCHEMBL8960246

SCHEMBL8960246

COc1c(C=O)cccc1OC(C)OC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
SRC P12931 1/20 0.49
TLR2 O60603 1/20 0.49
ERN1 O75460 1/20 0.49
TLR1 Q15399 1/20 0.49
TLR6 Q9Y2C9 1/20 0.49
NFE2L2 Q16236 6/20 0.44
CYP1A2 P05177 3/20 0.42
LMNA P02545 2/20 0.42
ALDH1A1 P00352 2/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
PRMT1 Q99873 1/20 0.42
KDM4E B2RXH2 2/20 0.40
HPGD P15428 2/20 0.40
ADRA2A P08913 1/20 0.40
ADRA2B P18089 1/20 0.40
ADRA2C P18825 1/20 0.40
NPC1 O15118 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3638137 0.88 CA1 (0.54) CA1CA2SRCTLR2ERN1
SCHEMBL11323988 0.84 ALDH1A1 (0.53) CA1CA2SRCTLR2ERN1
SCHEMBL8687904 0.83 CA1 (0.41) CA1CA2SRCTLR2ERN1
O-Veratraldehyde SCHEMBL29923149 0.82 SRC (0.67) CA1CA2SRCTLR2ERN1
O-Veratraldehyde SCHEMBL28289918 0.82 SRC (0.67) CA1CA2SRCTLR2ERN1
O-Veratraldehyde SCHEMBL319070 0.82 SRC (0.67) CA1CA2SRCTLR2ERN1
SCHEMBL2556391 0.81 KMT2A (0.58) CA1CA2SRCTLR2ERN1
SCHEMBL1253814 0.78 SRC (0.58) CA1CA2SRCTLR2ERN1
SCHEMBL2787203 0.78 CA1 (0.73) CA1CA2SRCTLR2ERN1
SCHEMBL1753794 0.78 CA1 (0.50) CA1CA2SRCTLR2ERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1120045-A New cephalosporins containing in position 7 a substituted benzyloxyimino radical, their preparation process, their use as medicaments ROUSSEL UCLAF (FR) 1996-04-10 CN disclosed
EP-0693496-A1 Novel cephalosporins having a substituted benzyloxyimino radical in position 7, process for their preparation and their use as medicaments ROUSSEL UCLAF (FR) 1996-01-24 EP disclosed