Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 2/20 | 0.47 |
| ▸ | TLR2 | O60603 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.47 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Methoxybenzaldehyde SCHEMBL5070004 | 0.89 | ALDH1A1 (0.54) | ALDH1A1HPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL177279 | 0.86 | ALDH1A1 (0.55) | ALDH1A1HPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL8960246 | 0.84 | CA1 (0.53) | ALDH1A1HPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL6706103 | 0.82 | ALDH1A1 (0.52) | ALDH1A1HPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL9723273 | 0.82 | ALDH1A1 (0.52) | ALDH1A1HPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL28570178 | 0.82 | ALDH1A1 (0.52) | ALDH1A1HPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL28061827 | 0.82 | ALDH1A1 (0.52) | ALDH1A1HPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL7762674 | 0.82 | ALDH1A1 (0.52) | ALDH1A1HPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL11384810 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL640294 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HPGDHTTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0027978-B1 | AMINO DERIVATIVES OF 5-(2-HYDROXYSTYRYL) ISOXAZOLE, METHODS FOR THEIR PREPARATION AND THERAPEUTICAL COMPOSITIONS CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1982-12-29 | — | — | EP | disclosed |
| EP-0005192-B1 | ALKYLAMINOPROPANOL DERIVATIVES OF 3-ALKYL-5-(2-HYDROXYSTYRYL)-ISOXAZOLES, PROCESSES FOR THEIR PREPARATION AND THERAPEUTICAL COMPOSITIONS CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1981-12-30 | — | — | EP | disclosed |
| EP-0005186-B1 | 3-ALKYL-5-(2-HYDROXYSTYRYL)-ISOXAZOLES AND PROCESS FOR THEIR PREPARATION | BASF Aktiengesellschaft (DE) | 1981-12-30 | — | — | EP | disclosed |
| US-4305951-A | TREATMENT OF HYPERTONIA, CORONARY HEART DISEASE AND CARDIAC ARRHYTHMIA | BASF AKTIENGESELLSCHAFT (DE) | 1981-12-15 | — | — | US | disclosed |
| EP-0034754-A1 | 2-((3-amino-2-hydroxy-propoxy)-styryl) isoxazoles, process for their preparation and pharmaceutical compositions containing them | BASF Aktiengesellschaft (DE) | 1981-09-02 | — | — | EP | disclosed |
| EP-0027978-A1 | Amino derivatives of 5-(2-hydroxystyryl) isoxazole, methods for their preparation and therapeutical compositions containing them | BASF Aktiengesellschaft (DE) | 1981-05-06 | — | — | EP | disclosed |
| US-4251539-A | HYPOTENSIVE AGENTS, ANTIARRHYTHMIA AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1981-02-17 | — | — | US | disclosed |
| EP-0005186-A1 | 3-Alkyl-5-(2-hydroxystyryl)-isoxazoles and process for their preparation | BASF Aktiengesellschaft (DE) | 1979-11-14 | — | — | EP | disclosed |
| EP-0005192-A1 | Alkylaminopropanol derivatives of 3-alkyl-5-(2-hydroxystyryl)-isoxazoles, processes for their preparation and therapeutical compositions containing them | BASF Aktiengesellschaft (DE) | 1979-11-14 | — | — | EP | disclosed |