Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8960581 | 0.71 | NAAA (0.48) | SMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL15241712 | 0.69 | NAAA (0.49) | SMN1; SMN2POLBNPSR1L3MBTL1 | |
| SCHEMBL8960176 | 0.69 | — | — | |
| SCHEMBL20221646 | 0.67 | SMN1; SMN2 (0.59) | SMN1; SMN2POLBNPSR1L3MBTL1PTPN1 | |
| SCHEMBL672908 | 0.65 | SMN1; SMN2 (0.96) | SMN1; SMN2POLBNPSR1L3MBTL1PTPN1 | |
| SCHEMBL16885251 | 0.63 | SMN1; SMN2 (0.53) | SMN1; SMN2POLBNPSR1L3MBTL1PTPN1 | |
| SCHEMBL16885249 | 0.63 | SMN1; SMN2 (0.53) | SMN1; SMN2POLBNPSR1L3MBTL1PTPN1 | |
| SCHEMBL10625541 | 0.63 | KMT2A (0.33) | SMN1; SMN2 | |
| SCHEMBL18731252 | 0.62 | SMN1; SMN2 (0.52) | SMN1; SMN2POLBNPSR1L3MBTL1PTPN1 | |
| SCHEMBL6159024 | 0.61 | PIK3CD (0.53) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0693058-A1 | IMPROVEMENTS IN OR RELATING TO CHIRAL AUXILIARIES | OXFORD ASYMMETRY LIMITED (GB) | 1996-01-24 | — | — | EP | disclosed |
| WO-1994024104-A1 | IMPROVEMENTS IN OR RELATING TO CHIRAL AUXILIARIES | OXFORD ASYMMETRY LIMITED (GB) | 1994-10-27 | — | — | WO | disclosed |