Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 3/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8960581 | 0.84 | NAAA (0.48) | L3MBTL1NPC1TDP1POLBHPGD | |
| SCHEMBL8960489 | 0.78 | HSD17B10 (0.46) | L3MBTL1HPGDCYP3A4ALDH1A1BRD4 | |
| SCHEMBL14540393 | 0.69 | NAAA (0.52) | L3MBTL1NPC1MEN1RAB9AKMT2A | |
| SCHEMBL14646662 | 0.68 | NPC1 (0.85) | L3MBTL1NPC1MEN1RAB9AKMT2A | |
| SCHEMBL14646675 | 0.68 | NPC1 (0.85) | L3MBTL1NPC1MEN1RAB9AKMT2A | |
| SCHEMBL8537851 | 0.68 | NAAA (0.48) | L3MBTL1NPC1TDP1POLBHPGD | |
| SCHEMBL7281001 | 0.68 | NAAA (0.57) | L3MBTL1NPC1TDP1POLBHPGD | |
| SCHEMBL9556953 | 0.68 | NAAA (0.57) | L3MBTL1NPC1TDP1POLBHPGD | |
| SCHEMBL7018288 | 0.68 | NAAA (0.50) | L3MBTL1NPC1TDP1POLBHPGD | |
| SCHEMBL16591625 | 0.66 | POLB (0.69) | L3MBTL1NPC1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0693058-A1 | IMPROVEMENTS IN OR RELATING TO CHIRAL AUXILIARIES | OXFORD ASYMMETRY LIMITED (GB) | 1996-01-24 | — | — | EP | disclosed |
| WO-1994024104-A1 | IMPROVEMENTS IN OR RELATING TO CHIRAL AUXILIARIES | OXFORD ASYMMETRY LIMITED (GB) | 1994-10-27 | — | — | WO | disclosed |