Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | STAT5B | P51692 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3379315 | 0.90 | HPGD (0.43) | ALDH1A1L3MBTL1MAPK1MAPTHPGD | |
| SCHEMBL192404 | 0.89 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1MAPT | |
| SCHEMBL7473118 | 0.84 | LTB4R2 (0.49) | ALDH1A1STAT5BSMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL29077734 | 0.82 | L3MBTL1 (0.50) | ALDH1A1L3MBTL1MAPK1MAPTHPGD | |
| SCHEMBL895556 | 0.82 | MLYCD (0.39) | ALDH1A1MLYCDSMN1; SMN2 | |
| SCHEMBL4832460 | 0.82 | ALDH1A1 (0.56) | LMNAALDH1A1MAPK1MAPTHPGD | |
| SCHEMBL7703626 | 0.81 | ALDH1A1 (0.49) | LMNAALDH1A1L3MBTL1MAPK1MAPT | |
| SCHEMBL1826174 | 0.81 | MLYCD (0.44) | ALDH1A1MAPTCA12CA7CA9 | |
| SCHEMBL5210280 | 0.80 | POLB (0.48) | ALDH1A1L3MBTL1MAPTSYKMLYCD | |
| SCHEMBL11651312 | 0.80 | ESR1 (0.45) | LMNAALDH1A1L3MBTL1HPGDSTAT5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593615-B1 | AROMATIC COMPOUNDS, COMPOSITIONS CONTAINING THEM AND THEIR USE IN THERAPY | MERCK SHARP & DOHME (GB) | 1996-01-31 | — | — | EP | claimed |