SCHEMBL5707571

SCHEMBL5707571

CO[C@H]1C[C@](O)(C(=O)c2ccccc2C)[C@H](C(O)C(=O)c2ccccc2C)O1

nearest known ligand 0.32

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 3/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
HTT P42858 2/20 0.32
ALDH1A1 P00352 2/20 0.31
CTNNB1 P35222 2/20 0.31
WNT3A P56704 2/20 0.31
KMT2A Q03164 1/20 0.30
ATM Q13315 1/20 0.30
PKM P14618 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5707632 1.00 P2RX7 (0.32) P2RX7SLC6A2SLC6A4SLC6A3NPC1
SCHEMBL4982728 1.00 P2RX7 (0.32) P2RX7SLC6A2SLC6A4SLC6A3NPC1
SCHEMBL4750928 0.90 SLC6A2 (0.31) P2RX7SLC6A2SLC6A4SLC6A3HTT
SCHEMBL3395341 0.85 HTT (0.33) P2RX7SLC6A2SLC6A4SLC6A3NPC1
SCHEMBL6842407 0.84 SLC6A2 (0.33) P2RX7SLC6A2SLC6A4SLC6A3NPC1
SCHEMBL2907033 0.84 SLC6A2 (0.33) P2RX7SLC6A2SLC6A4SLC6A3NPC1
SCHEMBL8960840 0.84 SLC6A2 (0.33) P2RX7SLC6A2SLC6A4SLC6A3NPC1
SCHEMBL5707587 0.84 SLC6A2 (0.33) P2RX7SLC6A2SLC6A4SLC6A3NPC1
SCHEMBL6844452 0.81 ALDH1A1 (0.39) NPC1RAB9AHTTALDH1A1KMT2A
SCHEMBL6843109 0.78 AR (0.44) NPC1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060229275-A1 Production method of 2-deoxy-L-ribofuranosyl chloride compound AJINOMOTO CO. INC (JP) 2006-10-12 US disclosed
EP-1705181-A2 Production method of 2-deoxy-L-ribofuranosyl chloride compound AJINOMOTO CO., INC. (JP) 2006-09-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060229275-A1 Production method of 2-deoxy-L-ribofuranosyl chloride compound DCTD, DERA, HDHD5 P2RX7 2082/4885SLC6A2 2300/4885SLC6A4 1792/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.