Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.49 |
| ▸ | DDO | Q99489 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 2/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10613155 | 0.82 | AOC3 (0.52) | DAODDOARFLT3AOC3 | |
| SCHEMBL28061062 | 0.81 | BRD4 (0.51) | DAOARFLT3AOC3KDM4E | |
| SCHEMBL8960942 | 0.77 | FLT3 (0.44) | DAODDOARFLT3AOC3 | |
| SCHEMBL1399629 | 0.77 | LOXL2 (0.49) | ARAOC3KDM4EGAAMAPT | |
| SCHEMBL6824543 | 0.76 | AR (0.49) | DAODDOARFLT3AOC3 | |
| SCHEMBL30990546 | 0.74 | AOC3 (0.52) | DAODDOARFLT3AOC3 | |
| SCHEMBL9328485 | 0.74 | AOC3 (0.52) | DAODDOARFLT3AOC3 | |
| SCHEMBL18427579 | 0.72 | AOC3 (0.50) | DAODDOARFLT3AOC3 | |
| SCHEMBL8427260 | 0.71 | AOC3 (0.48) | DAODDOARFLT3AOC3 | |
| SCHEMBL29258496 | 0.71 | AOC3 (0.48) | DAODDOARFLT3AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5567827-A | 4-Hydroxyphenylthio derivatives, their preparation and their use for the preparation of aminoalkoxyphenylsulphonyl derivatives | ELF SANOFI (FR) | 1996-10-22 | — | — | US | disclosed |
| US-5508431-A | 4-hydroxyphenylthio derivatives, their preparation and their use for the preparation of aminoalkoxyphenylsulphonyl derivatives | ELF SANOFI (FR) | 1996-04-16 | — | — | US | disclosed |
| US-5401855-A | 4-hydroxyphenylthio derivatives, their preparation and their use for the preparation of aminoalkoxyphenylsulphonyl derivatives | ELF SANOFI (FR) | 1995-03-28 | — | — | US | disclosed |