Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 11/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | F13A1 | P00488 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5339077 | 0.78 | MTNR1A (0.71) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7858 | 0.77 | KDM4E (0.69) | MTNR1AMTNR1BKMT2AMEN1LMNA | |
| SCHEMBL8851523 | 0.76 | MTNR1A (0.63) | MTNR1AMTNR1BKMT2AMEN1LMNA | |
| SCHEMBL5987986 | 0.76 | MTNR1A (0.63) | MTNR1AMTNR1BKMT2AL3MBTL1MEN1 | |
| Hydrochloric Acid SCHEMBL31736052 | 0.76 | KDM4E (0.67) | KMT2AL3MBTL1MEN1LMNATSHR | |
| SCHEMBL3887461 | 0.74 | POLB (0.55) | KMT2AL3MBTL1MEN1LMNATSHR | |
| SCHEMBL8229644 | 0.74 | MTNR1A (0.65) | MTNR1AMTNR1BKMT2AMEN1LMNA | |
| SCHEMBL422827 | 0.74 | L3MBTL1 (0.68) | MTNR1AMTNR1BKMT2AL3MBTL1CYP2C19 | |
| SCHEMBL5988458 | 0.74 | MTNR1A (0.65) | MTNR1AMTNR1BKMT2AMEN1LMNA | |
| SCHEMBL6638095 | 0.73 | POLB (0.59) | KMT2AL3MBTL1MEN1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593615-B1 | AROMATIC COMPOUNDS, COMPOSITIONS CONTAINING THEM AND THEIR USE IN THERAPY | MERCK SHARP & DOHME (GB) | 1996-01-31 | — | — | EP | disclosed |