Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.60 |
| ▸ | MME | P08473 | 5/20 | 0.60 |
| ▸ | CPA1 | P15085 | 5/20 | 0.60 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | ATM | Q13315 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | CTSD | P07339 | 4/20 | 0.56 |
| ▸ | REN | P00797 | 2/20 | 0.56 |
| ▸ | CTSS | P25774 | 3/20 | 0.56 |
| ▸ | CTSK | P43235 | 2/20 | 0.56 |
| ▸ | CTSL | P07711 | 1/20 | 0.56 |
| ▸ | CTSB | P07858 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8961015 | 1.00 | ACE (0.60) | ACEMMECPA1ACE2KMT2A | |
| SCHEMBL9754245 | 0.91 | CTSD (0.62) | ACEMMECPA1ACE2KMT2A | |
| SCHEMBL9754243 | 0.91 | CTSD (0.62) | ACEMMECPA1ACE2KMT2A | |
| SCHEMBL18257575 | 0.90 | CTSD (0.57) | ACEMMECPA1ACE2KMT2A | |
| SCHEMBL18257544 | 0.90 | CTSD (0.57) | ACEMMECPA1ACE2KMT2A | |
| SCHEMBL8130179 | 0.90 | KMT2A (0.67) | ACEKMT2AATMMEN1REN | |
| SCHEMBL29602242 | 0.90 | KMT2A (0.67) | ACEKMT2AATMMEN1REN | |
| SCHEMBL23616314 | 0.89 | CTSD (0.56) | KMT2AMEN1CTSDRENCTSS | |
| SCHEMBL18257547 | 0.89 | CTSD (0.56) | KMT2AMEN1CTSDRENCTSS | |
| SCHEMBL29484184 | 0.88 | KMT2A (0.66) | ACEKMT2AATMMEN1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119371478-A | Method for synthesizing amide and/or polypeptide by taking transient protection amino acid as ammonia component | 广州医科大学 | 2025-01-28 | — | — | CN | disclosed |
| WO-2025015659-A1 | METHOD FOR SYNTHESIZING AMIDE AND/OR POLYPEPTIDE BY TAKING TRANSIENTLY PROTECTED AMINO ACID AS AMMONIA COMPONENT | 广州医科大学 | 2025-01-23 | — | — | WO | disclosed |
| US-5480893-A | ANTITUMOR | MERCK & CO., INC. (US) | 1996-01-02 | — | — | US | disclosed |
| US-5340828-A | Anticarcinogenic agents | MERCK & CO., INC. (US) | 1994-08-23 | — | — | US | disclosed |
| EP-0535730-A2 | Inhibitors of farnesyl protein transferase | MERCK & CO. INC. (US) | 1993-04-07 | — | — | EP | disclosed |