Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 4/20 | 0.57 |
| ▸ | CTSS | P25774 | 3/20 | 0.57 |
| ▸ | CTSK | P43235 | 2/20 | 0.57 |
| ▸ | REN | P00797 | 5/20 | 0.56 |
| ▸ | ACE | P12821 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MME | P08473 | 1/20 | 0.52 |
| ▸ | CPA1 | P15085 | 1/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18257544 | 1.00 | CTSD (0.57) | CTSDCTSSCTSKRENACE | |
| SCHEMBL18257559 | 0.91 | CTSD (0.56) | CTSDCTSSCTSKRENKMT2A | |
| SCHEMBL18257555 | 0.91 | CTSD (0.56) | CTSDCTSSCTSKRENKMT2A | |
| SCHEMBL8961015 | 0.90 | ACE (0.60) | CTSDCTSSCTSKRENACE | |
| SCHEMBL8961019 | 0.90 | ACE (0.60) | CTSDCTSSCTSKRENACE | |
| SCHEMBL7137259 | 0.90 | CTSD (0.57) | CTSDCTSSCTSKRENACE | |
| SCHEMBL29709853 | 0.90 | BACE1 (0.57) | CTSDRENACEKMT2A | |
| SCHEMBL23616313 | 0.86 | REN (0.64) | CTSSCTSKRENACECTSL | |
| SCHEMBL18257495 | 0.86 | REN (0.64) | CTSSCTSKRENACECTSL | |
| SCHEMBL20825295 | 0.86 | REN (0.64) | CTSSCTSKRENACECTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3297678-B1 | AN IMPROVED PROCESSES FOR THE PREPARATION OF CARFILZOMIB OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | LAURUS LABS LTD (IN) | 2021-07-07 | — | — | EP | disclosed |
| WO-2016185450-A1 | AN IMPROVED PROCESSES FOR THE PREPARATION OF CARFILZOMIB OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | LAURUS LABS PRIVATE LIMITED (IN) | 2016-11-24 | — | — | WO | disclosed |