Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 4/20 | 0.62 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.59 |
| ▸ | REN | P00797 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CTSS | P25774 | 4/20 | 0.54 |
| ▸ | CTSK | P43235 | 3/20 | 0.54 |
| ▸ | CTSB | P07858 | 3/20 | 0.54 |
| ▸ | CTSL | P07711 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 2/20 | 0.49 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | CPA1 | P15085 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9754245 | 1.00 | CTSD (0.62) | CTSDKLK5RENALDH1A1THRB | |
| SCHEMBL23616314 | 0.92 | CTSD (0.56) | CTSDKLK5RENKMT2ACTSS | |
| SCHEMBL18257547 | 0.92 | CTSD (0.56) | CTSDKLK5RENKMT2ACTSS | |
| SCHEMBL8961019 | 0.91 | ACE (0.60) | CTSDRENKMT2ACTSSCTSK | |
| SCHEMBL8961015 | 0.91 | ACE (0.60) | CTSDRENKMT2ACTSSCTSK | |
| SCHEMBL7418843 | 0.90 | KLK5 (0.62) | CTSDKLK5RENALDH1A1THRB | |
| SCHEMBL9887475 | 0.90 | KLK5 (0.62) | CTSDKLK5RENALDH1A1THRB | |
| SCHEMBL27738325 | 0.90 | KLK5 (0.62) | CTSDKLK5RENALDH1A1THRB | |
| SCHEMBL9754315 | 0.88 | CTSS (0.57) | CTSDKLK5RENALDH1A1KMT2A | |
| SCHEMBL9754319 | 0.88 | CTSS (0.57) | CTSDKLK5RENALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991008221-A1 | PEPTIDE INHIBITORS OF HIV PROTEASE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1991-06-13 | — | — | WO | disclosed |