Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | CCR6 | P51684 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29293314 | 0.81 | ZDHHC20 (0.39) | ALDH1A1SLC6A2SLC6A4DPP4MEN1 | |
| SCHEMBL4621524 | 0.79 | PYCR1 (0.35) | ALDH1A1SMN1; SMN2LMNAHPGDCYP1A2 | |
| SCHEMBL88005 | 0.79 | ALDH1A1 (0.54) | ALDH1A1DPP4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18340467 | 0.79 | DPP4 (0.54) | ALDH1A1DPP4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11150408 | 0.77 | DPP4 (0.42) | ALDH1A1SLC6A2SLC6A4DPP4MEN1 | |
| SCHEMBL22960878 | 0.77 | ALDH1A1 (0.37) | ALDH1A1SLC6A2SLC6A4DPP4MEN1 | |
| SCHEMBL18746574 | 0.77 | ALDH1A1 (0.60) | ALDH1A1SLC6A2SLC6A4DPP4MEN1 | |
| SCHEMBL8985064 | 0.77 | ALDH1A1 (0.52) | ALDH1A1DPP4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9487258 | 0.77 | ALDH1A1 (0.52) | ALDH1A1DPP4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9245352 | 0.77 | ALDH1A1 (0.52) | ALDH1A1DPP4MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105461684-B | 3,4- dihydros -1H- [1,8] naphthyridones of cyclopenta [C] pyrroles substitution of antibacterial | 爱尔兰詹森科学公司 | 2018-09-25 | — | — | CN | disclosed |
| US-5554784-A | Process for preparing iodoalkynylcarbamates having a low tendency of yellowing when exposed to light | GRUENING RAINER (US) | 1996-09-10 | — | — | US | disclosed |