SCHEMBL8961313

SCHEMBL8961313

CC(C)(C)CC(C)(C)c1cc[c]c(C(C)(C)C)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.41
CYP3A4 P08684 3/20 0.36
CYP2D6 P10635 1/20 0.36
HIF1A Q16665 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.34
MEN1 O00255 1/20 0.33
USP2 O75604 1/20 0.33
ESR1 P03372 1/20 0.33
TP53 P04637 1/20 0.33
PGR P06401 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
AR P10275 1/20 0.33
MAPT P10636 1/20 0.33
DRD1 P21728 1/20 0.33
PTGS1 P23219 1/20 0.33
SLC6A2 P23975 1/20 0.33
PDE4A P27815 1/20 0.33
MAPK1 P28482 1/20 0.33
CASP1 P29466 1/20 0.33
SLC6A4 P31645 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5190093 0.91 SHBG (0.42) SHBGCYP3A4CYP2D6HIF1ASMN1; SMN2
SCHEMBL15068125 0.81 SHBG (0.44) SHBGCYP3A4CYP2D6HIF1ASMN1; SMN2
SCHEMBL226186 0.80 ALDH1A1 (0.38) MEN1MAPTKMT2A
SCHEMBL11817162 0.79 SHBG (0.42) SHBGCYP3A4CYP2D6HIF1ASMN1; SMN2
SCHEMBL27409495 0.78 ALDH1A1 (0.37) MEN1MAPTKMT2A
SCHEMBL28147188 0.78 ALDH1A1 (0.37) MEN1MAPTKMT2A
SCHEMBL28050955 0.78 ALDH1A1 (0.37) MEN1MAPTKMT2A
SCHEMBL28007764 0.78 ALDH1A1 (0.37) MEN1MAPTKMT2A
SCHEMBL28206151 0.78 ALDH1A1 (0.37) MEN1MAPTKMT2A
SCHEMBL4470598 0.78 ESR1 (0.35) CYP3A4HIF1AESR1ARSLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0487036-B1 Organic phosphites suitable as stabilizers and polymer compositions comprising them MONTELL NORTH AMERICA INC (US) 1996-02-07 EP claimed
US-5162548-A ORGANIC PHOSPHITES SUITABLE AS STABILIZERS FOR POLYMERS HIMONT INCORPORATED (US) 1992-11-10 US claimed
EP-0487036-A1 Organic phosphites suitable as stabilizers and polymer compositions comprising them MONTELL NORTH AMERICA INC. (US) 1992-05-27 EP claimed
EP-0487036-B1 Organic phosphites suitable as stabilizers and polymer compositions comprising them MONTELL NORTH AMERICA INC (US) 1996-02-07 EP disclosed
US-5326801-A Photoresistance, heat resistance, oxidation resistance HIMONT INCORPORATED (US) 1994-07-05 US disclosed
US-5162548-A ORGANIC PHOSPHITES SUITABLE AS STABILIZERS FOR POLYMERS HIMONT INCORPORATED (US) 1992-11-10 US disclosed
EP-0487036-A1 Organic phosphites suitable as stabilizers and polymer compositions comprising them MONTELL NORTH AMERICA INC. (US) 1992-05-27 EP disclosed