Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 4/20 | 0.37 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.37 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768450 | 0.94 | GABBR2 (0.42) | CNR1NPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL8961206 | 0.85 | KDM1A (0.51) | CNR1KDM1AMAOBSCN5ASCN10A | |
| SCHEMBL9159754 | 0.83 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL7751379 | 0.82 | NFE2L2 (0.47) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL7745489 | 0.82 | NFE2L2 (0.47) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL9061248 | 0.82 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL9061793 | 0.82 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL9156797 | 0.82 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL9159134 | 0.82 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL9156706 | 0.82 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0398155-B1 | Cyclopropylalkyl or cycloalkenyl compounds, process for their preparation and their use in liquid crystal mixtures | HOECHST AG (DE) | 1996-02-07 | — | — | EP | disclosed |
| US-5407599-A | Cyclopropylaklyl or -alkenyl or heterocyclic compounds, process for their preparation and their use in liquid-crystalline mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-04-18 | — | — | US | disclosed |