Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.40 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 5/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.39 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.37 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8961327 | 0.85 | CNR1 (0.40) | KDM1AMAOBCNR1SCN5ASCN10A | |
| SCHEMBL8768450 | 0.79 | GABBR2 (0.42) | KDM1AMAOBCNR1SCN5ASCN10A | |
| SCHEMBL9060474 | 0.79 | L3MBTL1 (0.49) | SCN5ASCN10AKCNH2SCN1ASCN9A | |
| SCHEMBL9060849 | 0.78 | L3MBTL1 (0.48) | SCN5ASCN10AKCNH2SCN1ASCN9A | |
| SCHEMBL9061793 | 0.77 | NPC1 (0.59) | SCN10A | |
| SCHEMBL9061111 | 0.77 | NPC1 (0.51) | SCN5ASCN10AKCNH2SCN1ASCN9A | |
| SCHEMBL9062349 | 0.75 | NPC1 (0.50) | SCN5ASCN10AKCNH2SCN1ASCN9A | |
| SCHEMBL9060178 | 0.75 | NPC1 (0.57) | SCN5A | |
| SCHEMBL9061842 | 0.75 | CHRNA7 (0.51) | SCN5ASCN10AKCNH2SCN1ASCN9A | |
| SCHEMBL14569995 | 0.74 | HPGD (0.44) | KDM1AMAOBPARP15PARP10PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0398155-B1 | Cyclopropylalkyl or cycloalkenyl compounds, process for their preparation and their use in liquid crystal mixtures | HOECHST AG (DE) | 1996-02-07 | — | — | EP | disclosed |
| US-5407599-A | Cyclopropylaklyl or -alkenyl or heterocyclic compounds, process for their preparation and their use in liquid-crystalline mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-04-18 | — | — | US | disclosed |