Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 12/20 | 0.62 |
| ▸ | ACHE | P22303 | 8/20 | 0.59 |
| ▸ | BCHE | P06276 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8131752 | 0.82 | MAOB (0.83) | MAOBACHEBCHE | |
| SCHEMBL9824940 | 0.82 | MAOB (0.83) | MAOBACHEBCHE | |
| SCHEMBL22778380 | 0.80 | ALDH1A1 (0.49) | ALDH1A1 | |
| SCHEMBL6789754 | 0.79 | ALDH1A1 (0.57) | ACHEALDH1A1 | |
| SCHEMBL8398570 | 0.78 | MAOB (0.84) | MAOBACHEBCHE | |
| SCHEMBL7571319 | 0.78 | ALDH1A1 (0.59) | ALDH1A1 | |
| SCHEMBL10725421 | 0.78 | L3MBTL1 (0.59) | ACHEALDH1A1 | |
| SCHEMBL19631329 | 0.78 | HDAC3 (0.47) | MAOBACHEBCHEALDH1A1 | |
| SCHEMBL21084263 | 0.77 | MAOB (1.00) | MAOBACHEBCHE | |
| SCHEMBL20780399 | 0.77 | ALDH1A1 (0.51) | ACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0693081-A1 | CYCLIC COMPOUNDS AND COMPOSITIONS WHICH INHIBIT BONE RESORPTION | Novartis AG (CH) | 1996-01-24 | — | — | EP | disclosed |
| WO-1994024153-A1 | CYCLIC COMPOUNDS AND COMPOSITIONS WHICH INHIBIT BONE RESORPTION | CIBA-GEIGY AG (CH) | 1994-10-27 | — | — | WO | disclosed |