SCHEMBL8961372

SCHEMBL8961372

C#CC(C)c1cc(N)c(F)cc1Cl

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10714228 0.76 APP (0.41) LMNA
SCHEMBL10553307 0.75 GAA (0.32) LMNATP53HTT
SCHEMBL8243764 0.75 GAA (0.35)
SCHEMBL8598834 0.73
SCHEMBL7689433 0.73 NPC1 (0.36)
SCHEMBL9234339 0.70 LMNA (0.33) LMNA
SCHEMBL9234352 0.69 LMNA (0.33) LMNA
SCHEMBL1477638 0.69 GAA (0.53) TP53
SCHEMBL14578394 0.69 GAA (0.53) TP53
SCHEMBL30573328 0.69 GAA (0.53) TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0554894-B1 Imine derivatives and process for production thereof SUMITOMO CHEMICAL CO (JP) 1996-02-07 EP disclosed
US-5256822-A Chemical intermediates for drugs and herbicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-10-26 US disclosed
EP-0554894-A2 Imine derivatives and process for production thereof SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1993-08-11 EP disclosed