Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8415231 | 0.84 | CYP19A1 (0.45) | ALDH1A1POLBMAPTSKP2CYP19A1 | |
| SCHEMBL8961346 | 0.82 | MAPT (0.49) | CYP3A4TP53MAOBTSHRFFAR1 | |
| SCHEMBL8364512 | 0.82 | MAOB (0.56) | CYP3A4TP53MAOBTSHRALDH1A1 | |
| SCHEMBL7569937 | 0.81 | MAOB (0.55) | CYP3A4TP53MAOBTSHRALDH1A1 | |
| SCHEMBL9297209 | 0.81 | ALDH1A1 (0.46) | TP53TSHRALDH1A1POLBHSP90AA1 | |
| SCHEMBL3151082 | 0.80 | MAOB (0.59) | CYP3A4TP53MAOBTSHRALDH1A1 | |
| SCHEMBL30994908 | 0.79 | MAOB (0.52) | CYP3A4TP53MAOBALDH1A1POLB | |
| SCHEMBL26102576 | 0.79 | MAOB (0.52) | CYP3A4TP53MAOBALDH1A1POLB | |
| SCHEMBL5604536 | 0.79 | MAOB (0.52) | CYP3A4TP53MAOBTSHRALDH1A1 | |
| SCHEMBL2997554 | 0.76 | ALDH1A1 (0.53) | CYP3A4TP53MAOBALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514748-A | POLYMER FOR SLIDING CONTAINING PHENOLIC RESINS AND LUBRICANTS WITH POLYIMIDES | MITSUI TOATSU CHEMICALS, INC. (JP) | 1996-05-07 | — | — | US | disclosed |