Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.39 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11242670 | 0.89 | HTT (0.59) | LMNAHTTTSHRKMT2AADRA1D | |
| SCHEMBL11556089 | 0.89 | LMNA (0.50) | LMNAHTTTSHRKMT2AADRA1D | |
| SCHEMBL20618032 | 0.85 | LMNA (0.51) | LMNAHTTTSHRKMT2AADRA1D | |
| SCHEMBL5255092 | 0.85 | HTT (0.52) | LMNAHTTTSHRKMT2AADRA1D | |
| Pramiracetam SCHEMBL195465 | 0.82 | LMNA (0.48) | LMNAHTTTSHRKMT2AADRA1D | |
| SCHEMBL9208885 | 0.81 | HTT (0.55) | LMNAHTTTSHRKMT2AADRA1D | |
| SCHEMBL11245716 | 0.81 | HTT (0.55) | LMNAHTTTSHRKMT2AADRA1D | |
| Pramiracetam SCHEMBL11556360 | 0.81 | LMNA (0.47) | LMNAHTTTSHRKMT2AADRA1D | |
| Pramiracetam SCHEMBL121209 | 0.81 | LMNA (0.47) | LMNAHTTTSHRKMT2AADRA1D | |
| SCHEMBL8961445 | 0.80 | TSHR (0.57) | LMNAHTTTSHRKMT2AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299495-B1 | 1-Pyrrolidineacetamide derivatives and use thereof | SANWA KAGAKU KENKYUSHO CO (JP) | 1996-02-07 | — | — | EP | disclosed |
| US-4939126-A | 1-pyrrolidineacetamide derivatives and use thereof | SANWA KAGAKU KENKYUSHO CO. LTD. (JP) | 1990-07-03 | — | — | US | disclosed |
| EP-0299495-A2 | 1-Pyrrolidineacetamide derivatives and use thereof | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1989-01-18 | — | — | EP | disclosed |