Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.68 |
| ▸ | DRD3 | P35462 | 3/20 | 0.65 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.65 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.65 |
| ▸ | HTR2B | P41595 | 1/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.65 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 2/20 | 0.64 |
| ▸ | DRD1 | P21728 | 2/20 | 0.64 |
| ▸ | DRD4 | P21917 | 2/20 | 0.64 |
| ▸ | CA9 | Q16790 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.64 |
| ▸ | CA12 | O43570 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA3 | P07451 | 1/20 | 0.64 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253650 | 0.90 | DRD2 (0.58) | DRD2DRD3ADRA2BADRA2CSLC6A4 | |
| SCHEMBL8961614 | 0.88 | DRD3 (0.68) | DRD2DRD3 | |
| SCHEMBL8961655 | 0.85 | DRD3 (0.60) | DRD2DRD3 | |
| SCHEMBL9423109 | 0.84 | DRD2 (0.53) | DRD2 | |
| SCHEMBL11054916 | 0.83 | DRD2 (0.80) | DRD2DRD3ADRA2BADRA2CSLC6A4 | |
| SCHEMBL11050065 | 0.81 | DRD2 (1.00) | DRD2DRD3ADRA2BADRA2CSLC6A4 | |
| Iodopride SCHEMBL9502371 | 0.81 | DRD2 (0.80) | DRD2DRD3ADRA2BADRA2CSLC6A4 | |
| Iodopride SCHEMBL10579084 | 0.81 | DRD2 (0.80) | DRD2DRD3ADRA2BADRA2CSLC6A4 | |
| SCHEMBL11046144 | 0.81 | DRD2 (1.00) | DRD2DRD3ADRA2BADRA2CSLC6A4 | |
| SCHEMBL11083117 | 0.81 | DRD2 (0.77) | DRD2DRD3ADRA2BADRA2CSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480631-A | Radioiodinated benzamines and method of their use as radioimaging | VANDERBILT UNIVERSITY (US) | 1996-01-02 | — | — | US | disclosed |
| EP-0317873-B1 | RADIOIODINATED BENZAMIDES AND METHOD OF THEIR USE AS RADIOIMAGING AGENTS | THE VANDERBILT UNIVERSITY (US) | 1993-05-12 | — | — | EP | disclosed |
| US-5154913-A | Detect, visualize, analyze distribution and function of dopamine receptors in brains | VANDERBILT UNIVERSITY (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0317873-A1 | Radioiodinated benzamides and method of their use as radioimaging agents | THE VANDERBILT UNIVERSITY (US) | 1989-05-31 | — | — | EP | disclosed |