SCHEMBL8961769

SCHEMBL8961769

Oc1c(I)cc(C2CCCCC2)cc1I

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 2/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
TTR P02766 2/20 0.42
CNR2 P34972 2/20 0.41
ACMSD Q8TDX5 2/20 0.41
HDAC4 P56524 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
KMO O15229 1/20 0.38
NOS3 P29474 2/20 0.36
NOS1 P29475 2/20 0.36
NOS2 P35228 2/20 0.36
ALB P02768 1/20 0.35
KMT2A Q03164 3/20 0.35
KDM4E B2RXH2 2/20 0.35
MEN1 O00255 2/20 0.35
MAPT P10636 1/20 0.35
CYP11B2 P19099 1/20 0.34
HTT P42858 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9622089 0.86 GABRA1 (0.43) HIF1ACYP2C9CYP2C19TTRCNR2
SCHEMBL18544650 0.81 CYP2C9 (0.43) HIF1ACYP2C9CYP2C19TTRCNR2
SCHEMBL28463897 0.78 ACHE (0.44) HIF1ACYP2C9CYP2C19CNR2ACMSD
SCHEMBL21307874 0.78 MAPT (0.35) CNR2ACMSDHDAC4HDAC2HDAC8
SCHEMBL28455121 0.78 ACHE (0.44) HIF1ACYP2C9CYP2C19CNR2ACMSD
SCHEMBL23514133 0.78 BACE1 (0.40) CNR2ACMSDHDAC4HDAC2HDAC8
SCHEMBL10883627 0.78 ACHE (0.44) HIF1ACYP2C9CYP2C19CNR2ACMSD
SCHEMBL7114890 0.78 ACHE (0.44) HIF1ACYP2C9CYP2C19CNR2ACMSD
SCHEMBL10884412 0.78 ACHE (0.44) HIF1ACYP2C9CYP2C19CNR2ACMSD
SCHEMBL5178585 0.78 ACHE (0.44) HIF1ACYP2C9CYP2C19CNR2ACMSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5558982-A High chloride (100) tabular grain emulsions with modified edge structures EASTMAN KODAK COMPANY (US) 1996-09-24 US disclosed
EP-0731379-A1 Photographic emulsions containing tabular grains with a band structure and a central grain portion of high bromide concentration EASTMAN KODAK COMPANY (US) 1996-09-11 EP disclosed
EP-0731378-A1 Emulsions with tabular grain major faces formed by regions of differing iodide concentrations EASTMAN KODAK COMPANY (US) 1996-09-11 EP disclosed
EP-0701166-A1 Grain growth process for the preparation of high bromide ultrathin tabular grain emulsions EASTMAN KODAK COMPANY (US) 1996-03-13 EP disclosed
EP-0694809-A1 A novel class of grain growth modifiers for the preparation of high chloride (111) tabular grain emulsions (II) EASTMAN KODAK COMPANY (US) 1996-01-31 EP disclosed
EP-0670514-A2 High chloride (100) tabular grain emulsions with modified edge structures EASTMAN KODAK COMPANY (US) 1995-09-06 EP disclosed