Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27698484 | 0.88 | CA1 (0.48) | GABRA1GABRB1GABRB2HIF1ACA1 | |
| SCHEMBL8961769 | 0.86 | HIF1A (0.42) | CYP2C9CYP2C19HIF1ACNR2ACMSD | |
| SCHEMBL27579601 | 0.81 | GABRA1 (0.43) | GABRA1GABRB1GABRB2CYP2C9CA1 | |
| SCHEMBL27579607 | 0.81 | GABRA1 (0.43) | GABRA1GABRB1GABRB2CYP2C9CYP2C19 | |
| SCHEMBL11223980 | 0.77 | ACMSD (0.54) | GABRA1GABRB1CYP2C9HIF1ACNR2 | |
| SCHEMBL28242980 | 0.75 | CNR2 (0.41) | GABRA1GABRB2CNR2ACMSDHSP90AA1 | |
| SCHEMBL27557639 | 0.74 | BACE1 (0.37) | ACMSDHSP90AA1GAA | |
| SCHEMBL3390002 | 0.73 | ACMSD (0.53) | GABRA1GABRB2ACMSDHSP90AA1HSP90AB1 | |
| SCHEMBL9516072 | 0.73 | APP (0.44) | CYP2C9CA1CA2HSP90AA1HSP90AB1 | |
| SCHEMBL12332702 | 0.71 | FABP3 (0.54) | CNR2ACMSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166171-A | Compounds for treatment of artheriosclerosis and hypercholesterolemia | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-11-24 | — | — | US | disclosed |