SCHEMBL8961865

SCHEMBL8961865

C=CCc1cc(I)c(O)c(I)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
XDH P47989 1/20 0.47
TNKS O95271 2/20 0.46
TNKS2 Q9H2K2 1/20 0.46
PARP1 P09874 1/20 0.46
GABRA1 P14867 6/20 0.45
GABRB2 P47870 6/20 0.45
ALDH1A1 P00352 4/20 0.45
PPARG P37231 2/20 0.45
PPARD Q03181 2/20 0.45
MEN1 O00255 2/20 0.45
GAA P10253 2/20 0.45
MAPT P10636 2/20 0.45
CNR1 P21554 2/20 0.45
CNR2 P34972 2/20 0.45
KMT2A Q03164 2/20 0.45
KDM4E B2RXH2 1/20 0.45
ALDH2 P05091 1/20 0.45
AKR1B1 P15121 1/20 0.45
HPGD P15428 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29538310 0.86 TNKS (0.63) TNKSTNKS2GABRA1GABRB2ALDH1A1
SCHEMBL719239 0.77 XDH (0.47) XDHTNKSTNKS2PARP1GABRA1
SCHEMBL2493537 0.76 TNKS (0.63) XDHTNKSTNKS2PARP1GABRA1
SCHEMBL2461750 0.74 XDH (0.48) XDHTNKSTNKS2PARP1GABRA1
SCHEMBL215399 0.74 XDH (0.50) XDHTNKSTNKS2PARP1GABRA1
SCHEMBL9167773 0.74 KDM4E (0.44) XDHTNKSTNKS2PARP1GABRA1
SCHEMBL1514254 0.73 XDH (0.52) XDHTNKSTNKS2PARP1GABRA1
SCHEMBL29064621 0.73 XDH (0.41) XDHTNKSTNKS2PARP1GABRA1
SCHEMBL6103705 0.73 TTR (0.50) ALDH1A1PPARGMEN1MAPTKMT2A
SCHEMBL4465266 0.73 XDH (0.52) XDHTNKSTNKS2PARP1GABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5558982-A High chloride (100) tabular grain emulsions with modified edge structures EASTMAN KODAK COMPANY (US) 1996-09-24 US disclosed
EP-0731379-A1 Photographic emulsions containing tabular grains with a band structure and a central grain portion of high bromide concentration EASTMAN KODAK COMPANY (US) 1996-09-11 EP disclosed
EP-0731378-A1 Emulsions with tabular grain major faces formed by regions of differing iodide concentrations EASTMAN KODAK COMPANY (US) 1996-09-11 EP disclosed
EP-0701166-A1 Grain growth process for the preparation of high bromide ultrathin tabular grain emulsions EASTMAN KODAK COMPANY (US) 1996-03-13 EP disclosed
EP-0694809-A1 A novel class of grain growth modifiers for the preparation of high chloride (111) tabular grain emulsions (II) EASTMAN KODAK COMPANY (US) 1996-01-31 EP disclosed
EP-0670514-A2 High chloride (100) tabular grain emulsions with modified edge structures EASTMAN KODAK COMPANY (US) 1995-09-06 EP disclosed