SCHEMBL4465266

SCHEMBL4465266

C=CCc1cc(O)cc(CC=C)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
XDH P47989 1/20 0.52
GABRA1 P14867 4/20 0.50
GABRB2 P47870 4/20 0.50
ALDH1A1 P00352 4/20 0.50
MAPT P10636 3/20 0.50
MEN1 O00255 2/20 0.50
GAA P10253 2/20 0.50
CNR1 P21554 2/20 0.50
CNR2 P34972 2/20 0.50
KMT2A Q03164 2/20 0.50
PPARG P37231 2/20 0.50
PPARD Q03181 2/20 0.50
KDM4E B2RXH2 1/20 0.50
ALDH2 P05091 1/20 0.50
AKR1B1 P15121 1/20 0.50
HPGD P15428 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
TNKS O95271 2/20 0.46
PARP1 P09874 1/20 0.46
CYP3A4 P08684 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1514254 0.95 XDH (0.52) XDHGABRA1GABRB2ALDH1A1MAPT
SCHEMBL14401171 0.91 ACHE (0.58) XDHGABRA1GABRB2ALDH1A1MAPT
SCHEMBL23854327 0.89 XDH (0.44) XDHGABRA1GABRB2ALDH1A1MAPT
SCHEMBL29859896 0.89 XDH (0.44) XDHGABRA1GABRB2ALDH1A1MAPT
SCHEMBL215399 0.86 XDH (0.50) XDHGABRA1GABRB2ALDH1A1MAPT
SCHEMBL13978619 0.84 XDH (0.44) XDHGABRA1GABRB2ALDH1A1MAPT
SCHEMBL8130202 0.84 CA12 (0.48) XDHGABRA1GABRB2ALDH1A1MAPT
SCHEMBL4420726 0.84 ALDH1A1 (0.48) XDHGABRA1GABRB2ALDH1A1MAPT
SCHEMBL31038513 0.84 XDH (0.44) XDHGABRA1GABRB2ALDH1A1MAPT
SCHEMBL6827660 0.80 CALM1 (0.54) GABRA1GABRB2ALDH1A1PPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110914341-B Method for producing modified lignin, and resin composition material containing modified lignin 出光兴产株式会社 2023-02-21 CN claimed
EP-3997464-A1 LIGANDS FOR CAPTURING MICROVESICLES AND USES THEREOF Université de Bordeaux (FR) 2022-05-18 EP claimed
WO-2021005167-A1 LIGANDS FOR CAPTURING MICROVESICLES AND USES THEREOF UNIVERSITÉ DE BORDEAUX (FR) 2021-01-14 WO claimed
EP-3394027-B1 METHOD FOR PREPARING PHENOLICS USING A CATALYST TNO (NL) 2020-02-19 EP claimed
US-10407376-B2 Method to prepare phenolics from biomass NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2019-09-10 US claimed
US-10364203-B2 Method for preparing phenolics using a catalyst NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2019-07-30 US claimed
US-20190002379-A1 Method for Preparing Phenolics Using a Catalyst NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2019-01-03 US claimed
EP-3394027-A1 METHOD FOR PREPARING PHENOLICS USING A CATALYST Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO (NL) 2018-10-31 EP claimed
US-20170349529-A1 Method to Prepare Phenolics from Biomass NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2017-12-07 US claimed
EP-3245186-A1 METHOD TO PREPARE PHENOLICS FROM BIOMASS Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO (NL) 2017-11-22 EP claimed
US-20160115347-A1 RESOLE PHENOLIC RESINS CURABLE WITH FUNCTIONAL POLYESTERS EASTMAN CHEMICAL COMPANY (US) 2016-04-28 US claimed
US-7547749-B2 Triazine compounds, polymers comprising triazine structural units, and method SABIC INNOVATIVE PLATICS IP B.V. (NL) 2009-06-16 US claimed
US-20080097040-A1 TRIAZINE COMPOUNDS, POLYMERS COMPRISING TRIAZINE STRUCTURAL UNITS, AND METHOD GENERAL ELECTRIC COMPANY (US) 2008-04-24 US claimed
US-20050192411-A1 Triazine compounds, polymers comprising triazine structural units, and method GENERAL ELECTRIC CO. 2005-09-01 US claimed
EP-1423372-A2 TRIAZINE COMPOUNDS, POLYMERS COMPRISING TRIAZINE STRUCTURAL UNITS, AND PROCESSES FOR THE PREPARATION OF THESE POLYMERS GENERAL ELECTRIC COMPANY (US) 2004-06-02 EP claimed
US-20030078347-A1 Triazine compounds, polymers comprising triazine structural units, and method GENERAL ELECTRIC COMPANY 2003-04-24 US claimed
WO-2003024939-A2 TRIAZINE COMPOUNDS POLYMERS COMPRISING TRIAZINE STRUCTURAL UNITS, AND PROCESSES FOR THE PREPARATION OF THESE POLYMERS GENERAL ELECTRIC COMPANY (US) 2003-03-27 WO claimed
US-5194563-A Polymeric species production HAY ALLAN S (CA) 1993-03-16 US claimed
US-4056568-A 2,6-Dialkyl-4-hydroxysulfenyl chlorides CROWN ZELLERBACH CORPORATION (US) 1977-11-01 US claimed
US-4046818-A SULFONATION KOPPERS COMPANY, INC. (US) 1977-09-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10407376-B2 Method to prepare phenolics from biomass FDPS, DNPH1, HPD XDH 962/4885GABRA1 3827/4885GABRB2 4000/4885
US-20170349529-A1 Method to Prepare Phenolics from Biomass FDPS, DNPH1, HPD XDH 962/4885GABRA1 3827/4885GABRB2 4000/4885
US-10364203-B2 Method for preparing phenolics using a catalyst TYR, FDPS, COMT XDH 352/4885GABRA1 4376/4885GABRB2 4533/4885
US-20190002379-A1 Method for Preparing Phenolics Using a Catalyst TYR, FDPS, COMT XDH 352/4885GABRA1 4376/4885GABRB2 4533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.