SCHEMBL8961913

SCHEMBL8961913

C=CC(=O)OC(C)OC(=O)Oc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.43
ALDH1A1 P00352 2/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
MAPT P10636 1/20 0.36
ELANE P08246 1/20 0.36
HCAR2 Q8TDS4 1/20 0.36
MEN1 O00255 1/20 0.36
LMNA P02545 1/20 0.36
TP53 P04637 1/20 0.36
GAA P10253 1/20 0.36
KMT2A Q03164 1/20 0.36
KDM4E B2RXH2 1/20 0.36
PDE6D O43924 1/20 0.36
MTNR1A P48039 4/20 0.36
MTNR1B P49286 4/20 0.36
TGM2 P21980 1/20 0.36
USP2 O75604 1/20 0.35
HTR1A P08908 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34034 0.82 THRB (0.46) THRBALDH1A1MAPTHCAR2MEN1
SCHEMBL29005896 0.81 THRB (0.45) THRBALDH1A1ATML3MBTL1ELANE
Water SCHEMBL28126876 0.81 THRB (0.45) THRBALDH1A1MAPTHCAR2MEN1
SCHEMBL8961892 0.81 THRB (0.43) THRBALDH1A1ATML3MBTL1MAPT
Acrylic Acid SCHEMBL28252917 0.79 THRB (0.44) THRBALDH1A1MAPTHCAR2MEN1
Acrylic Acid SCHEMBL7185233 0.79 THRB (0.44) THRBALDH1A1MAPTHCAR2MEN1
SCHEMBL8961851 0.79 THRB (0.44) THRBALDH1A1ATML3MBTL1MAPT
SCHEMBL8961889 0.78 ELANE (0.49) ALDH1A1ATML3MBTL1MAPTELANE
SCHEMBL449798 0.78 THRB (0.43) THRBALDH1A1MAPTHCAR2MEN1
SCHEMBL28010865 0.78 THRB (0.43) THRBALDH1A1HCAR2MEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7109336-A None JP disclosed
US-5488089-A Curable resin composition KANSAI PAINT CO., LTD. (JP) 1996-01-30 US disclosed
JP-H07109336-A CURABLE RESIN COMPOSITION KANSAI PAINT CO LTD 1995-04-25 JP disclosed