Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | PDE6D | O43924 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8961892 | 0.89 | THRB (0.43) | THRBTHRAZDHHC2PDE6DPOLB | |
| SCHEMBL7215636 | 0.88 | THRB (0.45) | THRBALDH1A1MAPTTP53KMT2A | |
| SCHEMBL12806617 | 0.86 | THRB (0.45) | THRBTHRAPOLBLMNASMN1; SMN2 | |
| SCHEMBL6360136 | 0.85 | THRB (0.44) | THRBTHRAPDE6DPOLBSMN1; SMN2 | |
| SCHEMBL3053163 | 0.85 | THRB (0.44) | THRBTHRAZDHHC2PPARGPPARA | |
| SCHEMBL10042216 | 0.84 | THRB (0.43) | THRBPOLBALDH1A1NPC1RAB9A | |
| SCHEMBL8961961 | 0.81 | TSHR (0.41) | THRBTHRAALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL9649938 | 0.81 | LMNA (0.44) | THRBTHRAALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL12246296 | 0.81 | BCL9 (0.38) | PPARGPPARAPOLBALDH1A1LMNA | |
| SCHEMBL1945993 | 0.80 | THRB (0.42) | THRBALDH1A1SMN1; SMN2TDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5488089-A | Curable resin composition | KANSAI PAINT CO., LTD. (JP) | 1996-01-30 | — | — | US | disclosed |