SCHEMBL8961892

SCHEMBL8961892

C=CC(=O)OC(CC)OC(=O)Oc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 4/20 0.43
THRA P10827 1/20 0.37
CYP1A2 P05177 1/20 0.36
ZDHHC2 Q9UIJ5 1/20 0.36
PDE6D O43924 1/20 0.36
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
ALDH1A1 P00352 3/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
POLB P06746 1/20 0.34
MIF P14174 1/20 0.34
FAAH O00519 1/20 0.34
ALOX15 P16050 1/20 0.34
MAPT P10636 2/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
ELANE P08246 1/20 0.34
LMNA P02545 1/20 0.34
TP53 P04637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8961851 0.89 THRB (0.44) THRBTHRACYP1A2ZDHHC2PDE6D
SCHEMBL218320 0.84 THRB (0.46) THRBTHRANPC1RAB9AALDH1A1
SCHEMBL8961913 0.81 THRB (0.43) THRBPDE6DALDH1A1MEN1KMT2A
SCHEMBL9650729 0.79 TSHR (0.45) THRBCYP1A2NPC1RAB9AALDH1A1
SCHEMBL28746111 0.79 POLB (0.40) THRBALDH1A1POLBL3MBTL1
SCHEMBL1110901 0.78 CYP3A4 (0.47) THRBTHRANPC1ALDH1A1MAPT
SCHEMBL7215636 0.78 THRB (0.45) THRBALDH1A1KMT2AMAPTL3MBTL1
SCHEMBL1138627 0.78 TSHR (0.45) THRBTHRAALDH1A1TP53TSHR
SCHEMBL23581937 0.77 RXRA (0.47) THRBMAPT
SCHEMBL23581933 0.76 MAPT (0.52) CYP1A2NPC1RAB9AMAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5488089-A Curable resin composition KANSAI PAINT CO., LTD. (JP) 1996-01-30 US disclosed