Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.64 |
| ▸ | HPGD | P15428 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.64 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.64 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.64 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15928126 | 0.93 | ALDH1A1 (0.70) | ALDH1A1KDM4EHPGDKMT2AHSD17B10 | |
| SCHEMBL8961859 | 0.92 | ALDH1A1 (0.72) | ALDH1A1KDM4EHPGDKMT2AHSD17B10 | |
| SCHEMBL9078491 | 0.83 | NPC1 (0.71) | ALDH1A1KDM4EHPGDKMT2AHSD17B10 | |
| SCHEMBL8175559 | 0.82 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDKMT2AHSD17B10 | |
| SCHEMBL31124704 | 0.82 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDKMT2AHSD17B10 | |
| SCHEMBL8961835 | 0.80 | ALDH1A1 (0.58) | ALDH1A1KDM4EHPGDKMT2AHSD17B10 | |
| SCHEMBL29627447 | 0.78 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDKMT2AHSD17B10 | |
| SCHEMBL1163801 | 0.78 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDKMT2AHSD17B10 | |
| SCHEMBL14176760 | 0.77 | KDM4E (1.00) | ALDH1A1KDM4EHPGDKMT2AHSD17B10 | |
| SCHEMBL31281633 | 0.77 | KDM4E (1.00) | ALDH1A1KDM4EHPGDKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516794-A | FOR THE TREATMENT OF BONE RESORPTION | INVERNI DELLA BEEFA S.P.A. (IT) | 1996-05-14 | — | — | US | claimed |
| EP-0586960-B1 | Xanthone derivatives, their preparation and use | INVERNI DELLA BEFFA SPA (IT) | 1996-02-07 | — | — | EP | claimed |
| EP-0586960-A1 | Xanthone derivatives, their preparation and use | INVERNI DELLA BEFFA S.P.A. (IT) | 1994-03-16 | — | — | EP | claimed |