Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.70 |
| ▸ | HPGD | P15428 | 5/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | TP53 | P04637 | 2/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.70 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.70 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.70 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8961918 | 0.93 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL8961859 | 0.88 | ALDH1A1 (0.72) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL11726836 | 0.84 | ALDH1A1 (0.71) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL29627447 | 0.83 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL1163801 | 0.83 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL9980172 | 0.82 | ALPG (0.53) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL10453911 | 0.80 | KDM4E (0.90) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL10453816 | 0.79 | ALDH1A1 (0.72) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL10452859 | 0.79 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL10454177 | 0.79 | KDM4E (0.88) | ALDH1A1KDM4EHPGDHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140220057-A1 | WT1 PEPTIDE CANCER VACCINE COMPOSITION FOR TRANSDERMAL ADMINISTRATION | INTERNATIONAL INSTITUTE OF CANCER IMMUNOLOGY, INC. (JP) | 2014-08-07 | — | — | US | disclosed |
| US-20140220059-A1 | WT1 PEPTIDE CANCER VACCINE COMPOSITION FOR MUCOSAL ADMINISTRATION | INTERNATIONAL INSTITUTE OF CANCER IMMUNOLOGY, INC. (JP) | 2014-08-07 | — | — | US | disclosed |
| US-20140220105-A1 | TAPE PREPARATION OF WT1 PEPTIDE CANCER VACCINE FOR TRANSDERMAL ADMINISTRATION | INTERNATIONAL INSTITUTE OF CANCER IMMUNOLOGY, INC. (JP) | 2014-08-07 | — | — | US | disclosed |
| US-20140220055-A1 | WT1 PEPTIDE CANCER VACCINE COMPOSITION FOR TRANSDERMAL ADMINISTRATION | INTERNATIONAL INSTITUTE OF CANCER IMMUNOLOGY, INC. (JP) | 2014-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140220105-A1 | TAPE PREPARATION OF WT1 PEPTIDE CANCER VACCINE FOR TRANSDERMAL ADMINISTRATION | TAP1, TAP2, MICA | ALDH1A1 4457/4885KDM4E 1692/4885HPGD 3953/4885 |
| US-20140220057-A1 | WT1 PEPTIDE CANCER VACCINE COMPOSITION FOR TRANSDERMAL ADMINISTRATION | TAP1, TAP2, MUC1 | ALDH1A1 4815/4885KDM4E 4099/4885HPGD 2869/4885 |
| US-20140220055-A1 | WT1 PEPTIDE CANCER VACCINE COMPOSITION FOR TRANSDERMAL ADMINISTRATION | TAP1, TAP2, MICA | ALDH1A1 4869/4885KDM4E 4028/4885HPGD 3038/4885 |
| US-20140220059-A1 | WT1 PEPTIDE CANCER VACCINE COMPOSITION FOR MUCOSAL ADMINISTRATION | MUC1, TAP1, MICA | ALDH1A1 4839/4885KDM4E 4038/4885HPGD 3391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.