Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 12/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.42 |
| ▸ | CNR1 | P21554 | 10/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3356610 | 0.99 | ALDH1A1 (0.49) | ALDH1A1CYP3A4HSD17B10HPGDNPC1 | |
| SCHEMBL501958 | 0.85 | CNR2 (0.49) | ALDH1A1HSD17B10HPGDSMN1; SMN2CNR2 | |
| SCHEMBL39060 | 0.85 | CNR2 (0.54) | CNR2CNR1 | |
| SCHEMBL22146182 | 0.84 | ALDH1A1 (0.58) | ALDH1A1CYP3A4HSD17B10HPGDNPC1 | |
| SCHEMBL10688950 | 0.84 | CNR2 (0.52) | CNR2CNR1 | |
| SCHEMBL10685133 | 0.82 | CNR2 (0.55) | CNR2CNR1 | |
| SCHEMBL10583140 | 0.82 | CNR2 (0.55) | CNR2CNR1 | |
| SCHEMBL10453098 | 0.81 | NPC1 (0.45) | ALDH1A1CYP3A4HSD17B10HPGDNPC1 | |
| SCHEMBL502238 | 0.81 | CNR2 (0.50) | CNR2CNR1 | |
| SCHEMBL30108338 | 0.81 | MAPT (0.46) | ALDH1A1CYP3A4HSD17B10HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512950-B1 | Substituted 1-aminonaphtalenes and stabilized compositions | CIBA GEIGY AG (CH) | 1996-01-17 | — | — | EP | claimed |
| EP-0512950-A1 | Substituted 1-aminonaphtalenes and stabilized compositions | CIBA-GEIGY AG (CH) | 1992-11-11 | — | — | EP | claimed |
| US-5160647-A | High temperature lubricants, heat and oxidation resistance | CIBA-GEIGY CORPORATION (US) | 1992-11-03 | — | — | US | claimed |
| EP-0512950-B1 | Substituted 1-aminonaphtalenes and stabilized compositions | CIBA GEIGY AG (CH) | 1996-01-17 | — | — | EP | disclosed |
| US-5244953-A | Polymers, oxidation and heat resistance | CIBA-GEIGY CORPORATION (US) | 1993-09-14 | — | — | US | disclosed |
| EP-0512950-A1 | Substituted 1-aminonaphtalenes and stabilized compositions | CIBA-GEIGY AG (CH) | 1992-11-11 | — | — | EP | disclosed |
| US-5160647-A | High temperature lubricants, heat and oxidation resistance | CIBA-GEIGY CORPORATION (US) | 1992-11-03 | — | — | US | disclosed |
| US-4394279-A | Antioxidant combinations of sulfur containing molybdenum complexes and aromatic amine compounds for lubricating oils | CHEVRON RESEARCH COMPANY (US) | 1983-07-19 | — | — | US | disclosed |
| US-4370246-A | Antioxidant combinations of molybdenum complexes and aromatic amine compounds | CHEVRON RESEARCH COMPANY (US) | 1983-01-25 | — | — | US | disclosed |
| US-4064059-A | ALIPHATIC ESTER, SUBSTITUTED 4-AMINO-TRIAZOLE, A PHENYLNAPHTHYLAMINE, DIALKYLDIPHENYLAMINE, HYDROCARBYL PHOSPHATE ESTER | TEXACO INC. (US) | 1977-12-20 | — | — | US | disclosed |