Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8962174 | 0.83 | GAA (0.41) | LMNASMN1; SMN2EPHX1ALDH1A1CYP3A4 | |
| SCHEMBL8746945 | 0.82 | CNR2 (0.43) | CNR1CNR2 | |
| SCHEMBL8962086 | 0.81 | ALDH1A1 (0.50) | NPC1RAB9ALMNASMN1; SMN2EPHX1 | |
| SCHEMBL3356610 | 0.80 | ALDH1A1 (0.49) | NPC1RAB9ALMNASMN1; SMN2EPHX1 | |
| SCHEMBL871745 | 0.78 | CDC25B (0.42) | RAB9ALMNAEPHX1ALDH1A1CYP3A4 | |
| SCHEMBL28838185 | 0.78 | ALDH1A1 (0.52) | NPC1RAB9AALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL1605213 | 0.77 | KDM4E (0.42) | RAB9ALMNAEPHX1ALDH1A1CYP3A4 | |
| SCHEMBL7004555 | 0.75 | NPC1 (0.49) | NPC1RAB9ALMNASMN1; SMN2EPHX1 | |
| SCHEMBL1604274 | 0.74 | EPHX1 (0.48) | NPC1RAB9ALMNASMN1; SMN2EPHX1 | |
| SCHEMBL1664994 | 0.74 | EPHX1 (0.48) | NPC1RAB9ALMNASMN1; SMN2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4954275-A | AND POLYMERS | CIBA-GEIGY CORPORATION (US) | 1990-09-04 | — | — | US | disclosed |
| US-4889883-A | POLYBUTADIENE, POLYISOPRENE, NEOPRENE, STYRENE BLOCK POLYMERS; LUBRICANTS | CIBA-GEIGY CORPORATION (US) | 1989-12-26 | — | — | US | disclosed |