Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 3/20 | 0.53 |
| ▸ | TTR | P02766 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | KDM5A | P29375 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 5/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2966509 | 0.87 | AHR (0.59) | AHRTTRCA1CA2MCL1 | |
| SCHEMBL20275953 | 0.84 | ESR1 (0.48) | TTRESR1KDM5AESR2MAOA | |
| SCHEMBL8962028 | 0.81 | ESR1 (0.49) | TTRESR1KDM5AESR2MAOA | |
| SCHEMBL1794501 | 0.80 | MAOA (0.63) | KDM5AMAOANPC1RAB9A | |
| SCHEMBL29465920 | 0.79 | TTR (0.71) | AHRTTRCA1CA2MCL1 | |
| SCHEMBL11728871 | 0.79 | TTR (0.71) | AHRTTRCA1CA2MCL1 | |
| SCHEMBL237891 | 0.78 | AHR (0.79) | AHRTTRCA1CA2MAOA | |
| SCHEMBL8961941 | 0.77 | TTR (0.59) | AHRTTRCA1CA2MCL1 | |
| SCHEMBL17827855 | 0.77 | MAPT (0.60) | ESR1KDM5AESR2CA12CA9 | |
| SCHEMBL584924 | 0.74 | CNR1 (0.44) | AHRTTRCA1CA2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516794-A | FOR THE TREATMENT OF BONE RESORPTION | INVERNI DELLA BEEFA S.P.A. (IT) | 1996-05-14 | — | — | US | disclosed |
| EP-0586960-B1 | Xanthone derivatives, their preparation and use | INVERNI DELLA BEFFA SPA (IT) | 1996-02-07 | — | — | EP | disclosed |
| EP-0586960-A1 | Xanthone derivatives, their preparation and use | INVERNI DELLA BEFFA S.P.A. (IT) | 1994-03-16 | — | — | EP | disclosed |