Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2395901 | 0.81 | ALDH1A1 (0.40) | NR1I2ALDH1A1LMNACYP2C9MIF | |
| SCHEMBL5144270 | 0.81 | HSD17B10 (0.37) | NR1I2ALDH1A1LMNACYP2C9MIF | |
| SCHEMBL6659198 | 0.74 | ESR1 (0.34) | NR1I2ALDH1A1LMNACYP2C9MIF | |
| SCHEMBL10616239 | 0.74 | — | — | |
| SCHEMBL9217122 | 0.73 | MAPT (0.39) | ALDH1A1LMNAALOX15HSD17B10 | |
| SCHEMBL1636904 | 0.72 | HSD17B3 (0.33) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL8775256 | 0.71 | — | — | |
| SCHEMBL197450 | 0.68 | — | — | |
| SCHEMBL28088249 | 0.65 | ACHE (0.31) | — | |
| SCHEMBL183348 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449216-B1 | 3,5-di-tertiarybutyl-4-hydroxyphenylmethylene derivatives of 2-substituted thiazolidinones, oxazolidinones, and imidazolidinones as antiinflammatory agents | WARNER LAMBERT CO (US) | 1996-02-07 | — | — | EP | disclosed |