⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL36416 | 0.81 | CA12 (0.33) | — | |
| SCHEMBL16720390 | 0.79 | HSD17B1 (0.48) | — | |
| SCHEMBL7261518 | 0.79 | — | — | |
| SCHEMBL3048684 | 0.77 | LTA4H (0.38) | — | |
| SCHEMBL15474744 | 0.77 | ICAM1 (0.36) | — | |
| SCHEMBL4858324 | 0.76 | CYP3A4 (0.33) | — | |
| SCHEMBL220664 | 0.74 | — | — | |
| SCHEMBL77754 | 0.74 | CA1 (0.39) | — | |
| SCHEMBL16167324 | 0.74 | PDE4B (0.39) | — | |
| SCHEMBL157754 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49934-E1 | Inhibitors of cellular metabolic processes | SERVIER PHARMACEUTICALS LLC (US) | 2024-04-23 | — | — | US | claimed |
| CN-109890822-B | Inhibitors of cellular metabolic processes | 安吉奥斯医药品有限公司 | 2022-08-30 | — | — | CN | claimed |
| US-11325914-B1 | Inhibitors of cellular metabolic processes | SERVIER PHARMACEUTICALS LLC (US) | 2022-05-10 | — | — | US | claimed |
| US-10800782-B2 | Inhibitors of cellular metabolic processes | Agios Pharmaceutical, Inc. (US) | 2020-10-13 | — | — | US | claimed |
| US-20200163933-A1 | INHIBITORS OF MICROBIALLY INDUCED AMYLOID | AXIAL BIOTHERAPEUTICS, INC. | 2020-05-28 | — | — | US | claimed |
| EP-3624782-A1 | INHIBITORS OF MICROBIALLY INDUCED AMYLOID | Axial Biotherapeutics, Inc. (US) | 2020-03-25 | — | — | EP | claimed |
| US-20190233424-A1 | INHIBITORS OF CELLULAR METABOLIC PROCESSES | SERVIER PHARMACEUTICALS LLC | 2019-08-01 | — | — | US | claimed |
| US-10329298-B2 | Inhibitors of cellular metabolic processes | AGIOS PHARMACEUTICALS, INC. (US) | 2019-06-25 | — | — | US | claimed |
| WO-2018213204-A1 | INHIBITORS OF MICROBIALLY INDUCED AMYLOID | AXIAL BIOTHERAPEUTICS, INC. (US) | 2018-11-22 | — | — | WO | claimed |
| US-20180079753-A1 | INHIBITORS OF CELLULAR METABOLIC PROCESSES | SERVIER PHARMACEUTICALS LLC | 2018-03-22 | — | — | US | claimed |
| US-20030187007-A1 | Inhibitors of protein kinase for the treatment of disease | LG BIOMEDICAL INSTITUTE | 2003-10-02 | — | — | US | claimed |
| US-20030162785-A1 | Protein kinase inhibitors | ABBVIE INC. | 2003-08-28 | — | — | US | claimed |
| US-20030119839-A1 | Protein kinase inhibitors | ABBOTT LABORATORIES | 2003-06-26 | — | — | US | claimed |
| WO-2003051838-A2 | PROTEIN KINASE INHIBITORS | ABBOTT LABORATORIES (US) | 2003-06-26 | — | — | WO | claimed |
| WO-2002096867-A2 | INHIBITORS OF PROTEIN KINASE FOR THE TREATMENT OF DISEASE | LG BIOMEDICAL INSTITUTE (US) | 2002-12-05 | — | — | WO | claimed |
| WO-2002067865-A2 | N-(ARYL)-2-ARYLETHENESULFONAMIDES AND THERAPEUTIC USES THEREOF | TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2002-09-06 | — | — | WO | claimed |
| EP-0778305-B1 | Hydroxyphenyl-containing polyorganosiloxanes | DOW CORNING TORAY SILICONE (JP) | 1999-04-07 | — | — | EP | claimed |
| US-5726271-A | Hydroxyphenyl-containing polyorganosiloxanes | DOW CORNING TORAY SILICONE, LTD. (JP) | 1998-03-10 | — | — | US | claimed |
| EP-0778305-A1 | Hydroxyphenyl-containing polyorganosiloxanes | Dow Corning Toray Silicone Company, Limited (JP) | 1997-06-11 | — | — | EP | claimed |
| EP-0413162-A2 | Novel cyclic acetals | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1991-02-20 | — | — | EP | claimed |