SCHEMBL8962161

SCHEMBL8962161

CCCCCC(C)(C)c1cc[c]c2ccccc12

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 17/20 0.35
CNR1 P21554 16/20 0.35
GPR55 Q9Y2T6 4/20 0.31
GPR18 Q14330 3/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8962159 0.80 SHBG (0.32)
SCHEMBL1371539 0.76 ALDH1A1 (0.35)
SCHEMBL11216774 0.75 CNR2 (0.43) CNR2CNR1GAA
SCHEMBL11445241 0.74 CNR2 (0.46) CNR2CNR1
SCHEMBL2127595 0.73 KDM4E (0.39) CNR2CNR1GAA
SCHEMBL10580580 0.72 CNR2 (0.40) CNR2CNR1GAA
SCHEMBL27615740 0.72 CNR2 (0.40) CNR2CNR1GAA
SCHEMBL2257428 0.71 LIPG (0.45) GAA
SCHEMBL5750515 0.71 LIPG (0.45) GAA
SCHEMBL9431976 0.71 CNR2 (0.36) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0512950-B1 Substituted 1-aminonaphtalenes and stabilized compositions CIBA GEIGY AG (CH) 1996-01-17 EP disclosed
US-5244953-A Polymers, oxidation and heat resistance CIBA-GEIGY CORPORATION (US) 1993-09-14 US disclosed
EP-0512950-A1 Substituted 1-aminonaphtalenes and stabilized compositions CIBA-GEIGY AG (CH) 1992-11-11 EP disclosed
US-5160647-A High temperature lubricants, heat and oxidation resistance CIBA-GEIGY CORPORATION (US) 1992-11-03 US disclosed