Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9072838 | 0.84 | ALDH1A1 (0.43) | GAACYP3A4LMNAACLYEGLN2 | |
| SCHEMBL21491422 | 0.81 | GAA (0.48) | GAATSHRLMNAACLYAKR1C3 | |
| SCHEMBL4425037 | 0.79 | ALDH1A1 (0.60) | GAAPOLBTSHRCYP3A4ACMSD | |
| SCHEMBL2517389 | 0.77 | ALDH1A1 (0.45) | GAAAPEX1POLBCYP3A4LMNA | |
| SCHEMBL5041907 | 0.77 | PDE4A (0.42) | GAAAPEX1KMT2A | |
| SCHEMBL16408484 | 0.76 | AKR1C3 (0.66) | APEX1POLBLMNAAKR1C3ALDH1A1 | |
| SCHEMBL1000570 | 0.76 | AKR1C3 (0.66) | APEX1POLBLMNAAKR1C3ALDH1A1 | |
| SCHEMBL3714450 | 0.76 | KMT2A (0.53) | TSHRNAMPTAKR1C3ALDH1A1MEN1 | |
| SCHEMBL30921570 | 0.74 | AKR1C3 (0.68) | APEX1POLBLMNAAKR1C3ALDH1A1 | |
| SCHEMBL2566255 | 0.74 | AKR1C3 (0.68) | APEX1POLBLMNAAKR1C3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5530130-A | DYEING PLASTICS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |
| EP-0639624-A1 | Phthaloperinone dyestuffs | BAYER AG (DE) | 1995-02-22 | — | — | EP | disclosed |