Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | APEX1 | P27695 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.55 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ACLY | P53396 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL65212 | 0.87 | APEX1 (0.67) | LMNAAPEX1POLBL3MBTL1CTDSP1 | |
| SCHEMBL29394064 | 0.87 | APEX1 (0.67) | LMNAAPEX1POLBL3MBTL1CTDSP1 | |
| SCHEMBL1397921 | 0.87 | APEX1 (0.67) | LMNAAPEX1POLBL3MBTL1CTDSP1 | |
| SCHEMBL29364883 | 0.87 | APEX1 (0.67) | LMNAAPEX1POLBL3MBTL1CTDSP1 | |
| SCHEMBL11611376 | 0.87 | LMNA (0.53) | LMNAAPEX1POLBL3MBTL1CTDSP1 | |
| SCHEMBL2807663 | 0.85 | TSHR (0.59) | LMNAAPEX1POLBL3MBTL1CTDSP1 | |
| SCHEMBL268999 | 0.85 | APEX1 (0.65) | LMNAAPEX1POLBL3MBTL1CTDSP1 | |
| SCHEMBL8999902 | 0.85 | APEX1 (0.70) | LMNAAPEX1POLBL3MBTL1CTDSP1 | |
| SCHEMBL7820979 | 0.84 | POLB (0.60) | LMNAAPEX1POLBL3MBTL1CTDSP1 | |
| SCHEMBL2679084 | 0.81 | MAPT (0.54) | LMNAAPEX1KMT2AFLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5530130-A | DYEING PLASTICS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |
| EP-0639624-A1 | Phthaloperinone dyestuffs | BAYER AG (DE) | 1995-02-22 | — | — | EP | disclosed |