Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9516048 | 0.86 | TSHR (0.57) | TSHRCASP1SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL7527853 | 0.86 | ALDH1A1 (0.58) | TSHRCASP1SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL8962319 | 0.85 | LMNA (0.56) | TSHRCASP1SMN1; SMN2LMNASLC16A1 | |
| SCHEMBL18577911 | 0.85 | TSHR (0.55) | TSHRCASP1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL1017989 | 0.85 | CA2 (0.56) | TSHRCASP1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL403618 | 0.85 | LMNA (0.74) | TSHRCASP1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL6554461 | 0.83 | HTR6 (0.56) | TSHRCASP1SMN1; SMN2LMNASLC16A1 | |
| Hydrochloric Acid SCHEMBL9651756 | 0.83 | LMNA (0.72) | TSHRCASP1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL1017556 | 0.82 | TSHR (0.52) | TSHRCASP1SMN1; SMN2LMNAPOLB | |
| SCHEMBL1397921 | 0.81 | APEX1 (0.67) | TSHRLMNASLC16A1APEX1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286353-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | FUJIFILM CORPORATION (JP) | 2010-11-11 | — | — | US | disclosed |
| CN-101868444-A | Acetylenic compound, salt thereof, condensate thereof, and composition thereof | FUJIFILM CORP | 2010-10-20 | — | — | CN | disclosed |
| US-20100240908-A1 | ACETYLENE COMPOUND | FUJIFILM CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |
| CN-101808982-A | Acetylene compound | FUJIFILM CORP | 2010-08-18 | — | — | CN | disclosed |
| EP-2202220-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | Fujifilm Corporation (JP) | 2010-06-30 | — | — | EP | disclosed |
| EP-2202221-A1 | ACETYLENE COMPOUND | Fujifilm Corporation (JP) | 2010-06-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240908-A1 | ACETYLENE COMPOUND | NAT1, KATNA1, KAT2B | TSHR 3644/4885CASP1 1288/4885SMN1; SMN2 2933/4885 |
| US-20100286353-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | KAT8, HDAC10, SSRP1 | TSHR 4692/4885CASP1 1789/4885SMN1; SMN2 2822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.