SCHEMBL8962336

SCHEMBL8962336

Cc1[c]c2[c]cccc2cc1

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 1/20 0.32
CYP1A2 P05177 1/20 0.32
CCR1 P32246 1/20 0.32
RAB9A P51151 1/20 0.32
CCR5 P51681 1/20 0.32
CYP2A6 P11509 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL60224 0.80 CYP2A6 (0.38) CYP1A2CCR1CCR5CYP2A6TDP1
SCHEMBL17044627 0.73 ALDH1A1 (0.31)
SCHEMBL2254594 0.68
SCHEMBL5693005 0.67 CYP2A6 (0.37) CYP1A2RAB9ACYP2A6TDP1
SCHEMBL65563 0.67 CYP2A6 (0.37) CYP1A2RAB9ACYP2A6TDP1
SCHEMBL512508 0.65 ALDH1A1 (0.30)
SCHEMBL17044576 0.65
SCHEMBL1928516 0.65
SCHEMBL1587165 0.64 ALDH1A1 (0.35) CYP1A2CYP2A6TDP1
SCHEMBL1071858 0.64 CYP1A2 (0.46) METAP2CYP1A2CCR1RAB9ACCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5530130-A DYEING PLASTICS BAYER AKTIENGESELLSCHAFT (DE) 1996-06-25 US disclosed