SCHEMBL60224

SCHEMBL60224

[c]1cccc2ccc[c]c12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.38
ALOX12 P18054 1/20 0.38
TSHR P16473 3/20 0.32
CYP3A4 P08684 2/20 0.32
ALDH1A1 P00352 2/20 0.32
HSD17B10 Q99714 2/20 0.32
CYP1A1 P04798 1/20 0.32
CYP1A2 P05177 1/20 0.32
HPGD P15428 1/20 0.32
CYP1B1 Q16678 1/20 0.32
TDP1 Q9NUW8 2/20 0.30
KDM4E B2RXH2 1/20 0.30
GMNN O75496 1/20 0.30
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30
HSP90AA1 P07900 1/20 0.30
MMP2 P08253 1/20 0.30
CYP2D6 P10635 1/20 0.30
MAPT P10636 1/20 0.30
MMP9 P14780 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1928516 0.82
SCHEMBL6860315 0.80
SCHEMBL8962336 0.80 METAP2 (0.32) CYP2A6CYP1A2TDP1CCR1CCR5
SCHEMBL17044627 0.80 ALDH1A1 (0.31) ALDH1A1HPGDMAPT
SCHEMBL452611 0.78 EGFR (0.30)
SCHEMBL453578 0.78 KDM4E (0.30) TSHRCYP3A4TDP1KDM4EGMNN
SCHEMBL15902373 0.76
SCHEMBL6482087 0.74 ALDH1A1 (0.36) TSHRCYP3A4ALDH1A1HSD17B10CYP1A1
SCHEMBL1587165 0.73 ALDH1A1 (0.35) CYP2A6ALOX12TSHRCYP3A4ALDH1A1
SCHEMBL2412853 0.72 ALDH1A1 (0.40) CYP2A6TSHRALDH1A1HSD17B10CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4631 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114423806-B Polyalkylene iminopolymers as dispersants 巴斯夫欧洲公司 2024-07-12 CN claimed
CN-113710652-B Compound, liquid crystal composition and liquid crystal display element 捷恩智株式会社 2024-06-21 CN claimed
CN-112979471-B Liquid crystal molecule horizontal alignment agent, liquid crystal composition and liquid crystal display element 捷恩智株式会社 2024-06-04 CN claimed
EP-4365180-A1 RARE EARTH COMPLEX Tosoh Corporation (JP) 2024-05-08 EP claimed
EP-3281238-B1 SEMICONDUCTING MATERIAL COMPRISING A PHOSPHINE OXIDE MATRIX AND METAL SALT NOVALED GMBH (DE) 2024-04-24 EP claimed
CN-117616032-A Rare earth complex 东曹株式会社 2024-02-27 CN claimed
CN-117586781-A Liquid crystal composition, liquid crystal display element and application thereof 捷恩智株式会社 2024-02-23 CN claimed
CN-112368260-B Compound, liquid crystal composition and liquid crystal display element 捷恩智株式会社 2024-02-20 CN claimed
CN-111408411-B Catalyst composition, preparation method thereof and application thereof in reaction of synthesizing 1-butene by ethylene selective dimerization 中国石油化工股份有限公司 2024-02-13 CN claimed
CN-111587237-B Compound, liquid crystal composition and liquid crystal display element 捷恩智株式会社 2023-12-29 CN claimed
EP-0241984-A2 Block polyesters having branched hydrophilic capping groups useful as soil release agents in detergent compositions THE PROCTER & GAMBLE COMPANY (US) 1987-10-21 EP claimed
EP-0187517-A2 High-temperature resistant, selectively developable resist EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1986-07-16 EP claimed
EP-0074559-B1 BETA-KETOAMIDES AND PIGMENT PREPARATIONS CONTAINING THESE AMIDES BASF Aktiengesellschaft (DE) 1985-01-23 EP claimed
US-4258121-A SULFONYLOXY N-SUBSTITUTED IMIDES AS PHOTOINITIATORS FUJI PHOTO FILM CO., LTD. (JP) 1981-03-24 US claimed
US-4150025-A COLORING TEIJIN LIMITED (JP) 1979-04-17 US claimed
US-4132715-A ISOMERIZATION OF AN ISOIMIDE CIBA-GEIGY CORPORATION (US) 1979-01-02 US claimed
US-4104194-A 1,2-FUSED 5- OR 6-MEMBERED 1,3-DINITROGEN HETEROCYCLIC COMPOUNDS AS ANTICORROSION AGENTS BAYER AKTIENGESELLSCHAFT (DE) 1978-08-01 US claimed
US-4077960-A YELLOW, POLYMERS TEIJIN LIMITED (JA) 1978-03-07 US claimed
US-4048174-A ANTI-CORROSION AGENTS BAYER AKTIENGESELLSCHAFT (DT) 1977-09-13 US claimed
US-3970649-A PIGMENTS SANDOZ LTD. (CH) 1976-07-20 US claimed