SCHEMBL896240

SCHEMBL896240

N#Cc1cccc2sc(C(=O)NC(=N)N)cc12

nearest known ligand 0.62

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 7/20 0.62
HDAC3 O15379 2/20 0.44
HDAC4 P56524 2/20 0.44
HDAC1 Q13547 2/20 0.44
HDAC7 Q8WUI4 2/20 0.44
HDAC2 Q92769 2/20 0.44
HDAC10 Q969S8 2/20 0.44
HDAC11 Q96DB2 2/20 0.44
HDAC8 Q9BY41 2/20 0.44
HDAC6 Q9UBN7 2/20 0.44
HDAC9 Q9UKV0 2/20 0.44
HDAC5 Q9UQL6 2/20 0.44
PLAU P00749 5/20 0.42
F9 P00740 3/20 0.42
F10 P00742 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.40
DYRK1A Q13627 1/20 0.38
DYRK1B Q9Y463 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL828832 0.94 SLC9A1 (0.67) SLC9A1
SCHEMBL31117978 0.82 SLC9A1 (0.72) SLC9A1PLAUF9F10DYRK1A
SCHEMBL829372 0.77 SLC9A1 (0.50) SLC9A1HDAC3HDAC4HDAC1HDAC7
SCHEMBL825790 0.76 SLC9A1 (1.00) SLC9A1
SCHEMBL2335640 0.76 SLC9A1 (0.54) SLC9A1PLAUF9F10
SCHEMBL828939 0.76 SLC9A1 (0.65) SLC9A1PLAU
SCHEMBL828437 0.76 SLC9A1 (0.65) SLC9A1L3MBTL1
SCHEMBL828380 0.76 SLC9A1 (0.49) SLC9A1PLAU
SCHEMBL829531 0.76 SLC9A1 (0.60) SLC9A1HDAC3HDAC4HDAC1HDAC7
SCHEMBL3505060 0.76 SLC9A1 (0.53) SLC9A1PLAUF9F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12533309-B2 Minoxidil adjuvant therapies CARING BRANDS, INC. (US) 2026-01-27 US disclosed
US-12527729-B2 Minoxidil adjuvant therapies CARING BRANDS, INC. (US) 2026-01-20 US disclosed
US-20250360128-A1 MINOXIDIL ADJUVANT THERAPIES JUPITER WELLNESS INC (US) 2025-11-27 US disclosed
EP-4536354-A1 MINOXIDIL ADJUVANT THERAPIES Jupiter Wellness, Inc. (US) 2025-04-16 EP disclosed
US-20240009101-A1 MINOXIDIL ADJUVANT THERAPIES Jupiter Wellness, Inc. (US) 2024-01-11 US disclosed
US-20230404886-A1 MINOXIDIL ADJUVANT THERAPIES Jupiter Wellness, Inc. (US) 2023-12-21 US disclosed
WO-2023239972-A1 MINOXIDIL ADJUVANT THERAPIES Jupiter Wellness, Inc. (US) 2023-12-14 WO disclosed
US-11766392-B2 Minoxidil adjuvant therapies Jupiter Wellness, Inc. (US) 2023-09-26 US disclosed
US-11628132-B2 Minoxidil adjuvant therapies Jupiter Wellness, Inc. (US) 2023-04-18 US disclosed
US-20220296486-A1 Minoxidil Adjuvant Therapies Jupiter Wellness, Inc. 2022-09-22 US disclosed
US-8793078-B2 Method for predicting activation energy using atomic fingerprint descriptor or atomic descriptor BIOINFORMATICS & MOLECULAR DESIGN RESEARCH CENTER (KR) 2014-07-29 US disclosed
EP-2674161-A1 FMO3 inhibitors for treating pain Akron Molecules GmbH (AT) 2013-12-18 EP disclosed
US-20130252924-A1 Compounds and Methods for Treating Pain AKRON MOLECULES GMBH (AT) 2013-09-26 US disclosed
EP-2633884-A1 Obesity small molecules Akron Molecules GmbH (AT) 2013-09-04 EP disclosed
US-20130030007-A1 Obesity Small Molecules AKRON MOLECULES GMBH (AT) 2013-01-31 US disclosed
US-20120084012-A1 METHOD FOR PREDICTING ACTIVATION ENERGY USING ATOMIC FINGERPRINT DESCRIPTOR OR ATOMIC DESCRIPTOR BIOINFORMATICS & MOLECULAR DESIGN RESEARCH CENTER (KR) 2012-04-05 US disclosed
US-20110213558-A1 METHOD FOR PREDICTING ACTIVATION ENERGY USING AN ATOMIC FINGERPRINT DESCRIPTOR OR AN ATOMIC DESCRIPTOR BIOINFORMATICS & MOLECULAR DESIGN RESEARCH CENTER (KR) 2011-09-01 US disclosed
EP-2354987-A2 METHOD FOR PREDICTING ACTIVATION ENERGY USING AN ATOMIC FINGERPRINT DESCRIPTOR OR AN ATOMIC DESCRIPTOR Bioinformatics&Molecular Design Research Center (KR) 2011-08-10 EP disclosed
WO-2011083150-A2 OBESITY SMALL MOLECULES AKRON MOLECULES GMBH (AT) 2011-07-14 WO disclosed
WO-2010056053-A2 METHOD FOR PREDICTING ACTIVATION ENERGY USING AN ATOMIC FINGERPRINT DESCRIPTOR OR AN ATOMIC DESCRIPTOR 사단법인 분자설계연구소 (KR) 2010-05-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12527729-B2 Minoxidil adjuvant therapies RXRA, RXRB, RXRG SLC9A1 236/4885HDAC3 2103/4885HDAC4 1267/4885
US-20130252924-A1 Compounds and Methods for Treating Pain TRPV1, ACHE, OPRL1 SLC9A1 2001/4885HDAC3 619/4885HDAC4 992/4885
US-12533309-B2 Minoxidil adjuvant therapies RXRG, RXRA, RXRB SLC9A1 357/4885HDAC3 2114/4885HDAC4 1804/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.