Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.34 |
| ▸ | PARP11 | Q9NR21 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | AKT2 | P31751 | 1/20 | 0.31 |
| ▸ | PRCP | P42785 | 1/20 | 0.30 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7756242 | 0.85 | PARP10 (0.33) | ESR2CYP2A6PARP10PARP11CYP1A2 | |
| SCHEMBL8962445 | 0.83 | NPC1 (0.35) | CYP1A2 | |
| SCHEMBL8962426 | 0.81 | CYP2A6 (0.45) | CYP2A6CYP2B6PARP10PARP11CYP1A2 | |
| SCHEMBL2964879 | 0.79 | ALDH1A1 (0.41) | PARP10PARP11PRCP | |
| SCHEMBL2973597 | 0.77 | MAOA (0.35) | ESR2CYP2A6CYP2B6MAOAMAOB | |
| SCHEMBL1826218 | 0.76 | CYP1A2 (0.32) | CYP1A2 | |
| SCHEMBL22228283 | 0.74 | CYP1A2 (0.31) | CYP1A2 | |
| SCHEMBL2967594 | 0.73 | MAOA (0.35) | ESR2CYP2A6CYP2B6MAOAMAOB | |
| SCHEMBL2969646 | 0.73 | ALDH1A1 (0.36) | ESR2PARP10PARP11MAOBPDCD1 | |
| SCHEMBL8962241 | 0.73 | GAA (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500005-B1 | Process for the preparation of substituted indenes | HOECHST AG (DE) | 1996-02-07 | — | — | EP | disclosed |
| US-5194619-A | PROCESS FOR THE PREPARATION OF SUBSTITUTED INDENES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-16 | — | — | US | disclosed |
| EP-0500005-A1 | Process for the preparation of substituted indenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-08-26 | — | — | EP | disclosed |