SCHEMBL2967594

SCHEMBL2967594

Cc1cc(-c2ccccc2)c2c(c1Br)CC=C2

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
ESR2 Q92731 1/20 0.34
CYP2A6 P11509 1/20 0.33
CYP2B6 P20813 1/20 0.33
ALDH1A1 P00352 2/20 0.32
MAPK1 P28482 1/20 0.32
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2973597 0.88 MAOA (0.35) MAOAMAOBESR2CYP2A6CYP2B6
SCHEMBL2960984 0.79 NUDT1 (0.30) MAOAMAOB
SCHEMBL2960039 0.79 ALDH1A1 (0.36) MAOAMAOBCYP2A6ALDH1A1MAPK1
SCHEMBL2972478 0.78 SKP2 (0.38) ALDH1A1MAPK1
SCHEMBL2974294 0.76
SCHEMBL2957707 0.76
SCHEMBL2960701 0.75 MAOA (0.34) MAOAMAOBALDH1A1
SCHEMBL2960704 0.75 PLA2G7 (0.33) ALDH1A1
SCHEMBL2969646 0.75 ALDH1A1 (0.36) MAOBESR2ALDH1A1MAPK1LMNA
SCHEMBL2972475 0.74 MAOA (0.31) MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7763562-B2 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-07-27 US disclosed
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2007-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization AP2M1, AP1M1, PYM1 MAOA 958/4885MAOB 902/4885ESR2 790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.