SCHEMBL8962569

SCHEMBL8962569

C=CS(C)(C)Cc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
PRSS1 P07477 2/20 0.41
PRSS2 P07478 2/20 0.41
PRSS3 P35030 2/20 0.41
FAAH O00519 1/20 0.41
ELANE P08246 1/20 0.41
PRTN3 P24158 1/20 0.41
CA5A P35218 1/20 0.41
CA9 Q16790 1/20 0.41
TP53 P04637 1/20 0.39
MMP1 P03956 1/20 0.38
MMP2 P08253 1/20 0.38
MMP9 P14780 1/20 0.38
MMP8 P22894 1/20 0.38
MMP13 P45452 1/20 0.38
MAOB P27338 1/20 0.37
KMT2A Q03164 1/20 0.36
CALM1 P0DP23 1/20 0.36
ALDH1A1 P00352 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19620709 0.74 CA1 (0.39) CA1CA2PRSS1PRSS2PRSS3
SCHEMBL1879853 0.73 CA2 (0.52) CA1CA2PRSS1PRSS2PRSS3
SCHEMBL2689672 0.73 CA2 (0.52) CA1CA2PRSS1PRSS2PRSS3
SCHEMBL22733727 0.72 CA2 (0.47) CA2KMT2AALDH1A1TSHRTDP1
SCHEMBL21732223 0.72 TSHR (0.45) CA2ALDH1A1TSHR
SCHEMBL22908217 0.72 CA1 (0.50) CA1CA2PRSS1PRSS2PRSS3
SCHEMBL1343355 0.72 CA1 (0.50) CA1CA2PRSS1PRSS2PRSS3
SCHEMBL11917653 0.70 CA2 (0.54) CA1CA2PRSS1PRSS2PRSS3
SCHEMBL22429350 0.69 CA1 (0.46) CA1CA2PRSS1PRSS2PRSS3
SCHEMBL92893 0.69 CA2 (0.58) CA1CA2PRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5580650-A CONTACTING POROUS SUPPORT WITH POLYMER SOLUTION, IRRADIATING THE POLYMER TO FORM FILM, FIXING THE FILM WITH GLUE LAYER TO SUPPORT THE DOW CHEMICAL COMPANY (US) 1996-12-03 US claimed
US-4877551-A Aqueous suspension of delaminated vermiculite HERCULES INCORPORATED (US) 1989-10-31 US claimed
JP-1130707-A None JP disclosed
CN-102791826-B Method for preparing photosensitive microparticles TRANSITIONS OPTICAL INC 2015-01-07 CN disclosed
US-5580650-A CONTACTING POROUS SUPPORT WITH POLYMER SOLUTION, IRRADIATING THE POLYMER TO FORM FILM, FIXING THE FILM WITH GLUE LAYER TO SUPPORT THE DOW CHEMICAL COMPANY (US) 1996-12-03 US disclosed
EP-0695437-A1 PHOTOCURABLE COMPOSITIONS THE DOW CHEMICAL COMPANY (US) 1996-02-07 EP disclosed
US-5464538-A Reverse osmosis membrane THE DOW CHEMICAL COMPANY (US) 1995-11-07 US disclosed
WO-1994024609-A2 PHOTOCURABLE COMPOSITIONS THE DOW CHEMICAL COMPANY (US) 1994-10-27 WO disclosed
US-5310581-A Photoresists, reacting photolabile onium with a photoreactive nucleophile, modified vinylbenzyl chloride polymer THE DOW CHEMICAL COMPANY (US) 1994-05-10 US disclosed
CN-1023866-C Composite polyamide reverse osmosis membrane and method for producing same DONALD CHEMICAL RAW MATERIAL C (US) 1994-02-23 CN disclosed
US-5238747-A Compounds with onium groups cured with compound having nucleophilic groups; photoresists release agents THE DOW CHEMICAL COMPANY (US) 1993-08-24 US disclosed
US-4812260-A INTERCALATING ORGANO-CATION SALTS INTO VERMICULITE UNDER SHEARING CONDITIONS HERCULES INCORPORATED (US) 1989-03-14 US disclosed
US-4797187-A COACERVATION OF CATIONS THE DOW CHEMICAL COMPANY (US) 1989-01-10 US disclosed
EP-0282928-A2 Process for production of mineral dispersions HERCULES INCORPORATED (US) 1988-09-21 EP disclosed
EP-0282093-A2 Aqueous suspension of delaminated vermiculite HERCULES INCORPORATED (US) 1988-09-14 EP disclosed
US-4769148-A Novel polyamide reverse osmosis membranes THE DOW CHEMICAL COMPANY (US) 1988-09-06 US disclosed
US-4704324-A REVERSE OSMOSIS, GAS SEPARATION, ULTRAFILTRATION THE DOW CHEMICAL COMPANY (US) 1987-11-03 US disclosed
WO-1987002682-A1 SEMI-PERMEABLE MEMBRANES PREPARED VIA REACTION OF CATIONIC GROUPS WITH NUCLEOPHILIC GROUPS THE DOW CHEMICAL COMPANY (US) 1987-05-07 WO disclosed
EP-0220660-A2 Semi-permeables membranes prepared via reaction of cationic groups with nucleophilic groups THE DOW CHEMICAL COMPANY (US) 1987-05-06 EP disclosed
US-4431768-A CATIONIC ADDITION POLYMERS CONTAINING SULFONIUM AND ISOTHIOURONIUM GROUPS THE DOW CHEMICAL COMPANY (US) 1984-02-14 US disclosed