Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | ELANE | P08246 | 1/20 | 0.52 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2689672 | 1.00 | CA2 (0.52) | CA2CA1PRSS1PRSS2PRSS3 | |
| SCHEMBL7202332 | 0.88 | APLNR (0.36) | CA2CA1PRSS1PRSS2PRSS3 | |
| SCHEMBL54603 | 0.84 | CA2 (0.35) | CA2CA1PRSS1PRSS2PRSS3 | |
| SCHEMBL7119214 | 0.79 | CA2 (0.54) | CA2CA1PRSS1PRSS2PRSS3 | |
| SCHEMBL8762405 | 0.79 | CA1 (0.33) | CA2CA1PRSS1PRSS2PRSS3 | |
| SCHEMBL15568272 | 0.78 | TGM2 (0.46) | CA2CA1CA9TSHRCA12 | |
| SCHEMBL11328330 | 0.78 | KMT2A (0.44) | KMT2AHPGDHSD17B10 | |
| SCHEMBL7716393 | 0.78 | RECQL (0.42) | CA2CA1CA5ACA9KMT2A | |
| SCHEMBL8434939 | 0.78 | TDP1 (0.50) | CA2CA1PRSS1PRSS2PRSS3 | |
| SCHEMBL15568501 | 0.78 | KMT2A (0.44) | CA2CA1CA9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3164702-B1 | USE OF FLUORESCENT POLYMERS IN MARKING COMPOSITIONS FOR THE DIAGNOSTIC DETERMINATION OF CLEANING PERFORMANCE | ECOLAB USA INC (US) | 2020-12-09 | — | — | EP | claimed |
| EP-0118983-B1 | TEXTILE TREATMENT | WOOL DEVELOPMENT INTERNATIONAL LIMITED (GB) | 1989-08-09 | — | — | EP | claimed |
| US-20240180158-A1 | COMPOUNDS HAVING SELECTIVE INACTIVATION ACTIVITY | UNIVERSITY OF NORTH CAROLINA AT WILMINGTON (US) | 2024-06-06 | — | — | US | disclosed |
| WO-2023003882-A2 | COMPOUNDS HAVING SELECTIVE INACTIVATION ACTIVITY | UNIVERSITY OF NORTH CAROLINA AT WILMINGTON (US) | 2023-01-26 | — | — | WO | disclosed |
| US-20150315174-A1 | Dendritic Molecular Intracellular Transporters and Methods of Making and Using Same | UNIV VANDERBILT (US) | 2015-11-05 | — | — | US | disclosed |
| US-8969622-B2 | Dendritic molecular intracellular transporters and methods of making and using same | VANDERBILT UNIVERSITY (US) | 2015-03-03 | — | — | US | disclosed |
| US-8492510-B2 | Multifunctional degradable nanoparticles with control over size and functionalities | VANDERBILT UNIVERSITY (US) | 2013-07-23 | — | — | US | disclosed |
| US-20110257343-A1 | Multifunctional Degradable Nanoparticles with Control over Size and Functionalities | VANDERBILT UNIVERSITY | 2011-10-20 | — | — | US | disclosed |
| US-7935782-B2 | Multifunctional degradable nanoparticles with control over size and functionalities | VANDERBILT UNIVERSITY (US) | 2011-05-03 | — | — | US | disclosed |
| US-20100317689-A1 | Prodrugs of proton pump inhibitors including the 1h-imidazo[4,5-b] pyridine moiety | ALEVIUM PHARMACEUTICALS, INC. | 2010-12-16 | — | — | US | disclosed |
| US-20100113524-A1 | Prodrugs of proton pump inhibitors including the (1h-pyrrol-1-yl)-1h-benzimidazole moiety | ALEVIUM PHARMACEUTICALS, INC. | 2010-05-06 | — | — | US | disclosed |
| US-7183367-B2 | Vinyl sulphone modified polymer | N.V. ORGANON (NL) | 2007-02-27 | — | — | US | disclosed |
| US-20040186256-A1 | Vinyl sulphone modified polymer | MERCK SHARP & DOHME B.V. (NL) | 2004-09-23 | — | — | US | disclosed |
| EP-1001997-B1 | VINYL SULPHONE MODIFIED POLYMER | AKZO NOBEL NV (NL) | 2003-03-26 | — | — | EP | disclosed |
| EP-1001997-A1 | VINYL SULPHONE MODIFIED POLYMER | Akzo Nobel N.V. (NL) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999007751-A1 | VINYL SULPHONE MODIFIED POLYMER | AKZO NOBEL N.V. (NL) | 1999-02-18 | — | — | WO | disclosed |
| US-4260552-A | INSECTICIDES, HERBICIDES | UNIROYAL, INC. (US) | 1981-04-07 | — | — | US | disclosed |
| US-4160846-A | Method for controlling insects with tetrasubstituted organotin compounds | UNIROYAL, INC. (US) | 1979-07-10 | — | — | US | disclosed |
| US-3971757-A | STABILIZERS FOR POLYMERS | CIBA-GEIGY CORPORATION (US) | 1976-07-27 | — | — | US | disclosed |
| US-3966711-A | 4-Alkyl-1,4-diaza-5-oxo-cycloheptanes and their 1-oxyls | CIBA-GEIGY CORPORATION (US) | 1976-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317689-A1 | Prodrugs of proton pump inhibitors including the 1h-imidazo[4,5-b] pyridine moiety | ABCB11, ATP6AP1, CYP4B1 | CA2 607/4885CA1 1685/4885PRSS1 270/4885 |
| US-20240180158-A1 | COMPOUNDS HAVING SELECTIVE INACTIVATION ACTIVITY | GAA, MGAM, GBA3 | CA2 1043/4885CA1 1028/4885PRSS1 280/4885 |
| US-20100113524-A1 | Prodrugs of proton pump inhibitors including the (1h-pyrrol-1-yl)-1h-benzimidazole moiety | ABCB11, ATP6AP1, PAH | CA2 825/4885CA1 2044/4885PRSS1 135/4885 |
| US-20150315174-A1 | Dendritic Molecular Intracellular Transporters and Methods of Making and Using Same | SLC18A2, SLC7A1, SLC18A3 | CA2 338/4885CA1 1308/4885PRSS1 3444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.