2-Pyrrolidone

2-Pyrrolidone

SCHEMBL8962586

O=C1CCCN1.O=S(O)(O)=S

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
OR51E2 Q9H255 1/20 0.68
CRBN Q96SW2 4/20 0.58
FKBP5 Q13451 1/20 0.58
KDM4E B2RXH2 2/20 0.41
GAA P10253 1/20 0.41
POLB P06746 1/20 0.41
GLA P06280 1/20 0.31
KMT2A Q03164 2/20 0.31
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Pyrrolidone SCHEMBL17061486 0.91 OR51E2 (0.75) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL27698786 0.91 OR51E2 (0.75) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL4966601 0.88 OR51E2 (0.71) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL8962584 0.86 OR51E2 (0.68) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL27503412 0.86 OR51E2 (0.68) OR51E2CRBNFKBP5KDM4EGAA
Sulfuric Acid SCHEMBL30278662 0.84 CRBN (0.76) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL4655461 0.83 OR51E2 (0.88) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL27729365 0.83
2-Pyrrolidone SCHEMBL3356160 0.83
2-Pyrrolidone SCHEMBL9304498 0.83 OR51E2 (1.00) OR51E2CRBNFKBP5KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5484691-A SUGAR ALCOHOL, THIOSULFATE, THIOCYANATE KONICA CORPORATION (JP) 1996-01-16 US disclosed