Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | CES2 | O00748 | 1/20 | 0.62 |
| ▸ | CES1 | P23141 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10691910 | 0.86 | CES2 (0.60) | SMN1; SMN2CES2CES1TP53ALDH1A1 | |
| SCHEMBL6632890 | 0.86 | TP53 (0.68) | SMN1; SMN2CES2CES1TP53ALDH1A1 | |
| SCHEMBL10341585 | 0.86 | CES2 (0.60) | SMN1; SMN2CES2CES1TP53ALDH1A1 | |
| SCHEMBL8962605 | 0.86 | ALDH1A1 (0.60) | SMN1; SMN2CES2CES1TP53ALDH1A1 | |
| SCHEMBL30192262 | 0.84 | NPC1 (0.63) | SMN1; SMN2CES2CES1TP53ALDH1A1 | |
| SCHEMBL4254988 | 0.84 | NPC1 (0.63) | SMN1; SMN2CES2CES1TP53ALDH1A1 | |
| SCHEMBL29964351 | 0.84 | TSHR (0.59) | SMN1; SMN2CES2CES1TP53ALDH1A1 | |
| SCHEMBL3571556 | 0.84 | MEN1 (0.63) | SMN1; SMN2CES2CES1TP53ALDH1A1 | |
| SCHEMBL11068069 | 0.84 | TSHR (0.69) | SMN1; SMN2CES2CES1TP53ALDH1A1 | |
| SCHEMBL11589885 | 0.84 | TSHR (0.59) | SMN1; SMN2CES2CES1TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0474501-B1 | Aromatic diamine compound, preparation process of same and polyimide prepared from same | MITSUI TOATSU CHEMICALS (JP) | 1996-02-14 | — | — | EP | disclosed |
| US-5322962-A | Produce polyimides with high heat and chemical resistance, processability | MITSUI TOATSU CHEMICALS, INC. (JP) | 1994-06-21 | — | — | US | disclosed |
| US-5231160-A | AROMATIC DIAMINE COMPOUND, PREPARATION PROCESS OF SAME AND POLYIMIDE PREPARED FROM SAME | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1993-07-27 | — | — | US | disclosed |
| EP-0474501-A1 | Aromatic diamine compound, preparation process of same and polyimide prepared from same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-03-11 | — | — | EP | disclosed |