SCHEMBL2168904

SCHEMBL2168904

C=C(C)C(=O)OCCC[Si](Cl)(CC)CC

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.56
THRB P10828 1/20 0.49
POLB P06746 1/20 0.40
APEX1 P27695 1/20 0.40
HTT P42858 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
ALDH1A1 P00352 3/20 0.35
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18037131 0.93 TSHR (0.62) TSHRTHRBPOLBAPEX1HTT
SCHEMBL27832270 0.88 TSHR (0.59) TSHRTHRBPOLBAPEX1HTT
SCHEMBL8962671 0.88 TSHR (0.64) TSHRTHRBPOLBAPEX1HTT
SCHEMBL2167888 0.86 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT
SCHEMBL8962606 0.85 TSHR (0.70) TSHRTHRBPOLBAPEX1HTT
SCHEMBL476606 0.84 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT
SCHEMBL22322552 0.84 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT
SCHEMBL4393500 0.82 TSHR (0.59) TSHRTHRBPOLBAPEX1HTT
SCHEMBL632865 0.82 TSHR (0.55) TSHRTHRBPOLBAPEX1HTT
SCHEMBL692374 0.82 TSHR (0.55) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1950239-B1 TRANSPARENT INORGANIC-OXIDE DISPERSION, RESIN COMPOSITION CONTAINING INORGANIC OXIDE PARTICLES, COMPOSITION FOR ENCAPSULATING LUMINESCENT ELEMENT, LUMINESCENT ELEMENT, HARD COAT, OPTICAL FUNCTIONAL FILM, OPTICAL PART, AND PROCESS FOR PRODUCING RESIN COMPOSITION CONTAINING INORGANIC OXIDE PARTICLES SUMITOMO OSAKA CEMENT CO LTD (JP) 2017-01-04 EP disclosed
US-9224928-B2 Light emitting element, light emitting device and electronic apparatus SEIKO EPSON CORPORATION (JP) 2015-12-29 US disclosed
CN-102040224-B Hydrophobic core-shell silica particle, hollow silica particle, and manufacturing methods thereof ADEKA CORP 2015-07-15 CN disclosed
US-20140332835-A1 LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE AND ELECTRONIC APPARATUS SEIKO EPSON CORPORATION (JP) 2014-11-13 US disclosed
US-20140206801-A1 INORGANIC OXIDE TRANSPARENT DISPERSION, RESIN COMPOSITION USED TO FORM TRANSPARENT COMPOSITE, TRANSPARENT COMPOSITE, AND OPTICAL MEMBER SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2014-07-24 US disclosed
EP-2752392-A1 INORGANIC OXIDE TRANSPARENT DISPERSION AND RESIN COMPOSITION FOR FORMING TRANSPARENT COMPOSITE, AND TRANSPARENT COMPOSITE AND OPTICAL MEMBER Sumitomo Osaka Cement Co., Ltd. (JP) 2014-07-09 EP disclosed
CN-103764567-A Inorganic oxide transparent dispersion and resin composition for forming transparent composite, and transparent composite and optical member SUMITOMO OSAKA CEMENT CO LTD 2014-04-30 CN disclosed
US-7985476-B2 Transparent zirconia dispersion and zirconia particle-containing resin composition, composition for sealing light emitting element and light emitting element, hard coat film and optical functional film and optical component, and method for producing zirconia particle-containing resin SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2011-07-26 US disclosed
CN-102040224-A Hydrophobic core-shell silica particle, hollow silica particle, and manufacturing methods thereof ADEKA CORP 2011-05-04 CN disclosed
US-20090140284-A1 Transparent Inorganic Oxide Dispersion and Iorganic Oxide Particle-Containing Resin Composition, Composition for Sealing Light Emitting Element and Light Emitting element, Hard Coat Film and Optical Functional Film and Optical Component, and Method for Producing Inorganic Oxide Pariticle-Containing Resin SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2009-06-04 US disclosed
CN-101296982-A Transparent inorganic-oxide dispersion, resin composition containing inorganic oxide particles, composition for encapsulating luminescent element, luminescent element, hard coat, optical functional fi SUMITOMO OSAKA CEMENT CO LTD (JP) 2008-10-29 CN disclosed
EP-1950239-A1 TRANSPARENT INORGANIC-OXIDE DISPERSION, RESIN COMPOSITION CONTAINING INORGANIC OXIDE PARTICLES, COMPOSITION FOR ENCAPSULATING LUMINESCENT ELEMENT, LUMINESCENT ELEMENT, HARD COAT, OPTICAL FUNCTIONAL FILM, OPTICAL PART, AND PROCESS FOR PRODUCING RESIN COMPOSITION CONTAINING INORGANIC OXIDE PARTICLES SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2008-07-30 EP disclosed
US-5554706-A LOW TEMPERATURE LIQUID CRYSTALS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1996-09-10 US disclosed
EP-0695770-A1 COPOLYMER HAVING LIQUID CRYSTAL GROUP IN THE SIDE CHAIN SAGAMI CHEMICAL RESEARCH CENTER (JP) 1996-02-07 EP disclosed
US-5190828-A Low-gloss polyacetal resin compositions and molded articles POLYPLASTICS CO., LTD. (JP) 1993-03-02 US disclosed