Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | USP5 | P45974 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | QDPR | P09417 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8962808 | 1.00 | KDM1A (0.36) | KDM1AMAOBHTR2AHTR2CHTR2B | |
| SCHEMBL8962654 | 0.95 | KDM1A (0.34) | KDM1AMAOBHTR2AHTR2CHTR2B | |
| SCHEMBL8963228 | 0.88 | P2RY14 (0.35) | KDM1AMAOBHDAC2SCD5 | |
| SCHEMBL8963237 | 0.88 | P2RY14 (0.35) | KDM1AMAOBHDAC2SCD5 | |
| SCHEMBL8962617 | 0.87 | SLC6A2 (0.35) | HDAC2CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8962613 | 0.87 | SLC6A2 (0.35) | HDAC2CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8962804 | 0.86 | KDM1A (0.44) | KDM1AHDAC2KCNH2 | |
| SCHEMBL8963266 | 0.86 | SLC6A3 (0.35) | HTR2CHDAC2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8962813 | 0.86 | KDM1A (0.44) | KDM1AHDAC2KCNH2 | |
| SCHEMBL8963272 | 0.86 | SLC6A3 (0.35) | HTR2CHDAC2SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559860-B1 | HALOVINYL-DERIVATIVES | HOFFMANN LA ROCHE (CH) | 1996-02-14 | — | — | EP | disclosed |
| US-5364556-A | Halovinyl-derivatives | HOFFMANN-LA ROCHE INC. (US) | 1994-11-15 | — | — | US | disclosed |