Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | TNKS | O95271 | 2/20 | 0.30 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963228 | 1.00 | P2RY14 (0.35) | P2RY14HDAC2KDM1ACYP17A1CYP11B2 | |
| Biphenyl SCHEMBL9450901 | 0.95 | NPC1 (0.41) | P2RY14HDAC2KDM1ACYP17A1CYP11B2 | |
| SCHEMBL8962836 | 0.89 | JAK2 (0.35) | HDAC2CYP11B2NPC1RAB9ACYP11B1 | |
| SCHEMBL8962842 | 0.89 | JAK2 (0.35) | HDAC2CYP11B2NPC1RAB9ACYP11B1 | |
| SCHEMBL9479282 | 0.88 | HDAC2 (0.35) | P2RY14HDAC2KDM1ACYP17A1CYP11B2 | |
| SCHEMBL9479289 | 0.88 | HDAC2 (0.35) | P2RY14HDAC2KDM1ACYP17A1CYP11B2 | |
| SCHEMBL9479286 | 0.88 | HDAC2 (0.35) | P2RY14HDAC2KDM1ACYP17A1CYP11B2 | |
| SCHEMBL8962808 | 0.88 | KDM1A (0.36) | HDAC2KDM1AMAOBSCD5 | |
| SCHEMBL8962817 | 0.88 | KDM1A (0.36) | HDAC2KDM1AMAOBSCD5 | |
| SCHEMBL8962846 | 0.87 | SLC6A3 (0.39) | HDAC2CYP3A4NPC1RAB9ATNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559860-B1 | HALOVINYL-DERIVATIVES | HOFFMANN LA ROCHE (CH) | 1996-02-14 | — | — | EP | disclosed |
| US-5364556-A | Halovinyl-derivatives | HOFFMANN-LA ROCHE INC. (US) | 1994-11-15 | — | — | US | disclosed |